China Factory Direct
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| CAS number | 2628280-48-6 |
| Product name | 3-Pyrrolidinepropanamide, α-amino-2-oxo-, hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor drug intermediates | Used as a key chiral intermediate in the synthesis of targeted anticancer drugs; participates in multi-step organic reactions to construct active molecular structures |
| Pharmaceutical R&D | Lead compound modification in new drug development | Applied for structural optimization to improve metabolic stability and bioavailability |
| Fine Chemicals | Synthesis of high-value-added chemicals | Employed in amide bond coupling or cyclization reactions to prepare complex nitrogen-containing heterocyclic compounds |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color and physical state (e.g., white to off-white crystalline powder); should conform to standard description. |
| Identification | Infrared Spectroscopy (IR) | Compare infrared spectrum with reference standard; characteristic absorption peaks must match to confirm molecular structure. |
| High-Performance Liquid Chromatography (HPLC) | Retention time matches that of the reference standard, used for preliminary structural confirmation. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Quantify main component using external standard or area normalization method; typically requires ≥98.0%–99.5%. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use gradient elution to separate and detect process impurities and degradation products; individual impurity ≤0.1%, total impurities ≤0.5%. |
| Water Content | Karl Fischer Titration | Determine water content in sample; typically controlled to ≤0.5%. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection to detect residual organic solvents from synthesis (e.g., methanol, ethanol, DMF). |
| Heavy Metals | Limit Test for Heavy Metals (Chinese Pharmacopoeia General Chapter) | Use thioacetamide method or ICP-MS to control total heavy metal content (e.g., ≤20 ppm). |
| pH Value (Solution) | pH Meter | Dissolve to a specified concentration (e.g., 1%) in water and measure pH; should fall within specified range (e.g., 4.0–6.0). |
| Melting Point | Capillary Melting Point Method | Determine melting temperature range to verify purity and crystal form consistency (e.g., 148–152°C). |
| Specific Optical Rotation | Polarimeter | Prepare solution at specified concentration and measure optical rotation; used to control optical purity of chiral compounds (e.g., [α]D²⁵). |
| Sulfated Ash / Residue on Ignition | Gravimetric Method | Weigh residue after high-temperature ignition of sample; controls inorganic impurities (e.g., ≤0.1%). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 182–186°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | +12.0 to +14.0° (c=1, 1M HCl) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.