China Factory Direct
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| CAS number | 263270-02-6 |
| Product name | 5-BROMO-3-PYRIDINECARBOXYLIC ACID TERT-BUTYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Structural building block for synthesizing anticancer, antiviral, and central nervous system (CNS) drugs | Used as a key brominated heterocyclic intermediate in palladium-catalyzed cross-coupling reactions—including Suzuki and Heck couplings—to construct the core scaffold of bioactive molecules |
| Agrochemical R&D | Structural modification precursor for novel insecticides and fungicides | Enables introduction of specific functional groups via substitution or transformation of the bromine atom to optimize binding affinity and selectivity toward target enzymes |
| Materials Science | Functionalized pyridine derivatives for organic light-emitting diodes (OLEDs) and organic field-effect transistors (OFETs) | Applied in deprotection, coupling, and cyclization steps to synthesize nitrogen-containing heteroaryl conjugated polymers or small-molecule optoelectronic materials |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities by comparing retention times and peak areas against reference standards or threshold limits. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, toluene) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based redox reaction in anhydrous medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni) after acid digestion by mass spectrometric detection of metal isotopes. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residual Tert-Butyl Alcohol | GC-FID | Detects residual t-BuOH by headspace GC-FID following sample equilibration and injection. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid under controlled heating rate per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles against established visual reference standards. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring weight loss after drying under specified temperature and vacuum conditions. |
| Acid Value | Acid-Base Titration | Quantifies free carboxylic acid groups by titration with standardized NaOH solution using phenolphthalein indicator. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light to confirm chiral integrity and absence of racemization. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 85–89°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.