China Factory Direct
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| CAS number | 26377-17-3 |
| Product name | ETHYL ISONICOTINOYLACETATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of intermediates for antitubercular drugs | Used as a precursor to isoniazid derivatives |
| Agrochemicals | Synthesis of intermediates for insecticides or herbicides | Applied to introduce active functional groups via esterification |
| Chemical Research | Organic synthesis reagent | Employed in the construction of heterocyclic compounds |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at ~220 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., unreacted isoniazid, ethyl acetate, hydrolysis products) via gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identifies and quantifies residual solvents (e.g., ethanol, ethyl acetate, toluene) using gas chromatography with flame ionization detection against internal/external standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Determines trace water content based on electrochemical iodine generation and stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (e.g., Pb, Cd, Ni, Fe) after acid digestion by detecting elemental mass-to-charge ratios with high sensitivity. |
| Chloride Impurity | Ion Chromatography (IC) | Quantifies chloride ions using suppressed conductivity detection after separation on an anion-exchange column. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity via thermal behavior. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Evaluates physical state (crystalline solid), clarity, and color intensity by visual comparison to standardized APHA color solutions. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light to confirm chiral integrity and absence of racemization (if applicable; compound is achiral, but method verifies identity/absence of chiral contaminants). |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by high-temperature incineration followed by precise weighing of residual non-volatile matter. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a standardized suspension (e.g., 1% w/v in water) to assess acidic/basic degradation products. |
| Bulk Density | ASTM D1895 | Determines mass per unit volume of freely settled powder using a calibrated cylinder and balance, reflecting handling and formulation properties. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution by analyzing angular scattering pattern of laser light passed through a dispersed sample. |
| Microbial Limits | Membrane Filtration / Plate Count | Detects and enumerates aerobic microorganisms (total viable count, yeasts/molds) using selective media and incubation per pharmacopeial guidelines (e.g., USP <61>). |
| Test Item | Specification |
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| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 78-82°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic ester-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.