China Factory Direct
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| CAS number | 264927-52-8 |
| Product name | 2-Chloro-4-fluoro-5-iodo-benzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of anticancer agents (e.g., EGFR inhibitors) and candidate drug molecules containing fluorinated iodinated aryl motifs | Serves as a key aryl halide building block in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck); incorporated into the core scaffold of drug molecules via derivatization such as esterification and amidation |
| Agrochemical R&D | Serves as a structural lead compound for novel fluorinated iodinated benzoic acid–based fungicides or insecticides | Functional group transformations—including halogen exchange, nitration/reduction, and diazotization—are employed to construct biologically active heterocyclic derivatives |
| Materials Science | Used in the preparation of liquid crystal display materials and functional molecules for electron-transport layers in organic light-emitting diode (OLED) devices | Acts as a terminal modification unit for rigid biphenyl or terphenyl structures; coupled into conjugated polymer backbones or small-molecule charge-transport materials |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient reverse-phase HPLC with UV detection. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents by gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (e.g., Pb, Cd, Hg) via inductively coupled plasma mass spectrometry for high sensitivity and multi-element capability. |
| Water Content | Karl Fischer Titration | Determines water content by coulometric or volumetric titration based on iodine-sulfur dioxide reaction stoichiometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection. |
| Iodine Content | ICP-OES | Quantifies total iodine by measuring characteristic atomic emission lines after acid digestion and plasma excitation. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity via thermal behavior. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled lighting against established reference standards. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing and weighing. |
| Acid Value | Acid-Base Titration | Determines carboxylic acid concentration by titration with standardized NaOH solution using phenolphthalein indicator. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution by analyzing angular scattering pattern of laser light passing through dispersed sample. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 172-176°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.