Methyl Benzimidazole-5-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 26663-77-4 |
| Product name | Methyl Benzimidazole-5-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl Benzimidazole-5-carboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl Benzimidazole-5-carboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl Benzimidazole-5-carboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate for synthesizing antiparasitic drugs (e.g., albendazole, mebendazole) | Used as a key raw material to prepare benzimidazole anthelmintics via condensation and cyclization reactions |
| Pesticide Industry | Intermediate for preparing fungicides and insecticides | Applied in pesticide synthesis as a structural unit for constructing the benzimidazole ring system, followed by functionalization to yield active ingredients |
| Materials Science | Synthesis of organic ligands or functional molecules | Employed as a precursor to prepare functional components in metal–organic frameworks (MOFs) or polymeric materials |
Manufacturing Quality Control of Methyl Benzimidazole-5-carboxylate
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance and Physical Characteristics | Visual Inspection + Physical Property Measurement | Observe sample color and state (typically white to off-white crystalline powder), determine melting point (literature value approximately 165–170°C), conforming to pharmacopoeial or company specifications. |
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Use C18 column with mobile phase of methanol-water or acetonitrile-phosphate buffer, UV detector (254 nm or 280 nm), external standard method for quantification. Calculate the area percentage of the main peak; typically requires ≥98.0%. |
| Related Substances (Impurity Profile) | HPLC (Gradient Elution) | Employ gradient elution program to separate possible synthetic intermediates and by-products (e.g., benzimidazole, 5-carboxylic acid, ester hydrolysis products). Detection limit usually ≤0.1%, with individual and total impurities reported within specified limits. |
| Solvent Residues | Gas Chromatography (GC) | Use headspace injection or direct injection with FID detection. Detect residual organic solvents (e.g., methanol, ethanol, ethyl acetate, DMF), controlled within PDE limits according to ICH Q3C guidelines. |
| Moisture Content | Karl Fischer Titration (Karl Fischer) | Determine trace moisture using volumetric or coulometric Karl Fischer titration. Controlled at ≤0.5% (can be relaxed to 1.0% depending on application) to ensure stability and crystalline form. |
| Melting Point | Digital Melting Point Apparatus | Determine melting range using a digital melting point instrument. Should match literature values (~165–170°C) with deviation ≤2°C, used for preliminary identification and purity assessment. |
| UV Absorption Spectrum | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Prepare solution in ethanol or methanol, scan from 200–400 nm, record maximum absorption wavelength (λmax ≈ 270–280 nm) and absorbance ratio, used for structural confirmation and auxiliary quantification. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After ashing or digestion, determine levels of lead, cadmium, mercury, arsenic, etc., complying with ICH Q3D or pharmacopoeial limits (e.g., lead ≤5 ppm). |
| Inorganic Impurities (e.g., Chloride, Sulfate) | Colorimetry or Ion Chromatography | Perform chloride and sulfate limit tests according to general pharmacopoeial procedures, using turbidimetry or ion chromatography for quantification, ensuring inorganic impurities meet injection-grade or raw material standards. |
| Polymorphism (if applicable) | X-Ray Powder Diffraction (XRPD) | Used to confirm crystalline form (polymorph), ensuring consistency with reference standard, avoiding potential impact of polymorphic differences on solubility and stability—especially critical for formulation raw materials. |
| pH Value (Aqueous Solution) | pH Meter Measurement | Prepare a 1% aqueous solution of the sample and measure pH (typically neutral to slightly acidic, pH 5.5–7.5), used to evaluate acidity/basicity effects on stability. |
Technical Specifications of Methyl Benzimidazole-5-carboxylate
| Test Item | Specification |
|---|---|
| Appearance | Pale-purple solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 152–156 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl Benzimidazole-5-carboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl Benzimidazole-5-carboxylate
Safety Information of Methyl Benzimidazole-5-carboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl Benzimidazole-5-carboxylate
Industrial Methyl Benzimidazole-5-carboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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