China Factory Direct
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| CAS number | 26699-00-3 |
| Product name | N-CARBOBENZOXY-L-ISOLEUCINE DICYCLOHEXYLAMMONIUM SALT |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical Synthesis | Used as an amino acid protecting group for synthesizing peptide drug intermediates | Applied in peptide synthesis as the benzyloxycarbonyl (Z)-protected form of L-isoleucine; introduced into the peptide chain via coupling reactions, followed by deprotection to yield the target peptide |
| Biopharmaceuticals | Used to synthesize bioactive peptides or drug precursors | Employed as a key monomer in solid-phase or solution-phase peptide synthesis for constructing peptide chains, suitable for targeted drug development |
| Chemical Research | Used as a reference reagent for studying reaction characteristics of amino acid derivatives | Applied to investigate the stability, selectivity, and conversion efficiency of protected amino acids under varying reaction conditions |
| Advanced Materials | Used in synthesizing functional peptide-based materials, such as self-assembling peptide nanostructures | Processed via controlled polymerization and modification to produce functional biomaterials for applications including drug delivery and tissue engineering |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess determination using a chiral stationary phase with UV detection, resolving L-isoleucine derivative from its D-enantiomer. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., methanol, ethyl acetate) based on retention time and flame ionization response. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water via iodine-sulfur dioxide reaction in anhydrous pyridine-methanol medium. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and plasma excitation. |
| Residue on Ignition | Gravimetric Analysis | Mass measurement of inorganic ash remaining after high-temperature incineration at 500-600 C. |
| pH (1% w/v aqueous solution) | pH Meter | Measurement of hydrogen ion activity in a standardized aqueous suspension using calibrated glass electrode. |
| Specific Optical Rotation | [alpha]D | Determination of chiral compound’s ability to rotate plane-polarized light at 589 nm using a digital polarimeter. |
| Related Substances | HPLC-UV | Detection and quantification of structurally similar impurities (e.g., deprotected isoleucine, benzyl alcohol, diastereomers) using gradient elution. |
| Counterion (Dicyclohexylammonium) Content | Ion-Pair HPLC or NMR | Quantitative analysis of dicyclohexylammonium cation via retention time matching or proton integration relative to reference. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution based on angular scattering intensity of laser light. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic mesophilic microorganisms and detection of specified pathogens following pharmacopeial filtration and incubation protocols. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Optical Rotation | +4.0 to +4.5° (c=1, in DMF) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.