1-Bromo-3,4,5-trimethoxybenzene Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2675-79-8 |
| Product name | 1-Bromo-3,4,5-trimethoxybenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-Bromo-3,4,5-trimethoxybenzene
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Bromo-3,4,5-trimethoxybenzene Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Bromo-3,4,5-trimethoxybenzene
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Synthesis of Trimethoxybenzaldehyde (TMB) | Serves as a key intermediate in formylation reactions (e.g., Vilsmeier-Haack reaction) to introduce an aldehyde group, yielding 3,4,5-trimethoxybenzaldehyde for the synthesis of sulfonamide potentiators (e.g., trimethoprim). |
| Pharmaceutical Chemicals | Synthesis of Trimethoxybenzoic Acid and Derivatives | Oxidized to produce 3,4,5-trimethoxybenzoic acid, followed by esterification or amidation to generate ester- or amide-based derivatives used as pharmaceutical intermediates. |
| Pharmaceutical Chemicals | Synthesis of the Antibacterial Potentiator Trimethoprim (TMP) | Used as a starting material in multi-step reactions—including formylation, condensation, and cyclization—to construct the pyrimidine ring, ultimately yielding trimethoprim. |
| Pharmaceutical Chemicals | Synthesis of the Coronary Vasodilator Trimetazidine | Acts as an intermediate in the synthesis of piperazine derivatives for the production of trimetazidine hydrochloride. |
| Organic Synthesis | Construction of Biphenyl or Stilbene Derivatives | Leverages bromine reactivity in Suzuki or Heck coupling reactions with arylboronic acids or alkenes to construct complex biphenyl or styrene-type structures. |
| Organic Synthesis | Preparation of Alcohols or Carboxylic Acids via Grignard Reaction | Converted into the corresponding Grignard reagent (1-bromo-3,4,5-trimethoxyphenylmagnesium bromide), then reacted with carbonyl compounds or carbon dioxide to yield alcohols or carboxylic acids. |
| Dye Industry | Synthesis of Trimethoxyaniline | Subjected to amination to replace the bromo group with an amino group, producing 3,4,5-trimethoxyaniline as an intermediate for azo dyes and other functional pigments. |
Manufacturing Quality Control of 1-Bromo-3,4,5-trimethoxybenzene
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies main component peak area relative to calibration standard using flame ionization detection. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separates and quantifies impurities based on retention time and UV absorbance at 254 nm. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling | Detects and quantifies volatile organic solvents by equilibrium partitioning into headspace gas phase. |
| Moisture Content | Karl Fischer Titration | Measures water content via stoichiometric reaction between water, iodine, and sulfur dioxide in pyridine/methanol medium. |
| Acid Value | Acid-Base Titration with NaOH | Determines acidic impurities by titration with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Heavy Metals | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Quantifies trace metal contaminants (e.g., Pb, Cd, Hg) by atomic emission intensity after plasma atomization. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and detects chloride ions based on anion exchange retention and conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of particulates or foreign matter under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light induced by chiral impurities or degradation products. |
| Residue on Ignition | Gravimetric Analysis | Determines non-volatile inorganic residue after high-temperature ashing and weighing. |
| pH of Aqueous Solution | pH Meter Measurement | Measures hydrogen ion activity in saturated aqueous suspension using calibrated glass electrode. |
Technical Specifications of 1-Bromo-3,4,5-trimethoxybenzene
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 72–76°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-Bromo-3,4,5-trimethoxybenzene
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-Bromo-3,4,5-trimethoxybenzene
Safety Information of 1-Bromo-3,4,5-trimethoxybenzene
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-Bromo-3,4,5-trimethoxybenzene
Industrial 1-Bromo-3,4,5-trimethoxybenzene Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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