China Factory Direct
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| CAS number | 26774-89-0 |
| Product name | (R)-(+)-alpha-[(3-Methoxy-1-methyl-3-oxo-1-propenyl)amino]-1,4-cyclohexadiene-1-acetic acid sodium salt |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceutical Manufacturing | Synthesis of β-lactam antibiotics | Used as a key intermediate in the synthesis of cephalosporin- and penicillin-class antibiotics to enhance drug stability and antimicrobial activity |
| Chemical Synthesis | Chiral synthesis reagent | Applied as a chiral auxiliary or precursor to chiral catalysts in asymmetric synthesis for constructing chiral centers |
| Research & Development | New drug development | Applied in molecular design and synthetic route optimization for novel antibacterial agents |
| Industrial Catalysis | Asymmetric catalytic reactions | Used as part of chiral ligands or catalysts in asymmetric hydrogenation, oxidation, and related reactions |
| Biochemistry | Enzyme inhibitor research | Applied in studies of specific enzyme inhibition mechanisms, particularly in antibiotic resistance research |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-2-Amino-2-phenylacetic acid D-sodium salt content) | HPLC with UV detection | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV absorbance at 210 nm. |
| Related Substances | HPLC with UV detection | Separation and quantification of impurities (e.g., L-isomer, benzaldehyde, glycine derivatives) relative to main peak using gradient elution and UV detection. |
| Water Content | Karl Fischer titration | Electrochemical titration measuring water via reaction of iodine with sulfur dioxide in pyridine/methanol medium. |
| Residue on Ignition | Gravimetric analysis | Mass loss after high-temperature incineration (700-800 C) followed by weighing of inorganic residue. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification of heavy metals (Pb, Cd, Hg, As, Cr) after acid digestion using plasma optical emission spectroscopy. |
| Chloride Content | Potentiometric titration with AgNO3 | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| Sodium Content | Flame Photometry | Measurement of sodium-specific emission intensity at 589 nm in an air-propane flame after sample atomization. |
| Optical Rotation | [alpha]D | Measurement of plane-polarized light rotation in solution using a calibrated polarimeter at 20 C and sodium D-line (589 nm). |
| pH (1% aqueous solution) | pH meter measurement | Electrochemical determination of hydrogen ion activity using calibrated glass and reference electrodes in a 1% w/v aqueous solution. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity versus angle to calculate volume-based particle size distribution in a dispersed slurry. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic mesophilic microorganisms after filtration, membrane transfer to agar media, and incubation at 30-35 C for 3-5 days. |
| Organic Volatile Impurities (residual solvents) | GC-FID | Separation and quantification of residual solvents (e.g., methanol, acetone, ethyl acetate) using capillary GC with flame ionization detection. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Optical Rotation | +12.0 to +14.0° (c=1, in 1M HCl) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.