2-Methyl-4-isothiazolin-3-one Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2682-20-4 |
| Product name | 2-Methyl-4-isothiazolin-3-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Methyl-4-isothiazolin-3-one
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Methyl-4-isothiazolin-3-one Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Methyl-4-isothiazolin-3-one
| Industry | Application | Process |
|---|---|---|
| Personal Care & Cosmetics | Preservative | Added to aqueous formulations such as shampoos, body washes, and skin care products to inhibit bacterial and fungal growth |
| Coatings & Paints | Preservative & Anti-mildew Agent | Added during waterborne coating production to prevent microbial contamination and degradation during storage |
| Pulp & Paper | Biocide | Applied in the wet-end system to control microbial proliferation, preventing paper deterioration and biofilm formation on equipment |
| Industrial Water Treatment | Microbial Control | Injected into recirculating systems such as cooling water and cleaning solutions to suppress bacterial, algal, and fungal growth |
| Adhesives & Sealants | Preservation | Used as a preservative additive in aqueous adhesive manufacturing to extend product shelf life |
| Cleaners & Detergents | Preservative Ingredient | Employed in liquid household and industrial cleaners to prevent spoilage caused by microbial growth |
Manufacturing Quality Control of 2-Methyl-4-isothiazolin-3-one
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Content Determination | HPLC (High-Performance Liquid Chromatography) | Uses a C18 reversed-phase chromatography column, with methanol-water or acetonitrile-water as the mobile phase, and a UV detector operating at wavelengths of 230–250 nm. Quantification is performed using external or internal standard methods, offering high selectivity and accuracy. This method is commonly used in pharmacopoeias and industrial standards. |
| Purity Analysis | LC-MS (Liquid Chromatography-Mass Spectrometry) | Combines HPLC separation with mass spectrometry detection to simultaneously determine MIT and potential impurities (e.g., methylchloroisothiazolinone, degradation products), providing molecular weight and structural information. Suitable for high-purity raw material quality control. |
| Moisture Determination | Karl Fischer Titration | Utilizes a reaction between iodine, sulfur dioxide, pyridine, and methanol under specific conditions with water, quantitatively determining trace moisture content in the sample. Used to control moisture levels in MIT raw materials to prevent hydrolysis and degradation. |
| Chloride Impurity Detection | Ion Chromatography (IC) | Separates chloride ions (from chlorinated impurities such as MCT) using an anion exchange column, and quantifies them using a conductivity detector. Suitable for detecting residual chloride impurities during MIT production. |
| Solvent Residue Detection | Gas Chromatography (GC) | Uses headspace or direct injection, with an FID detector, to detect residual organic solvents (e.g., ethanol, acetone, DMF) from the production process. Complies with ICH Q3C guidelines for residual solvents. |
| Melting Point Determination | Melting Point Measurement | Determines the melting point of MIT (literature value approximately 75–78°C) using capillary or automatic melting point apparatus. Used for preliminary identification and purity assessment; a narrow melting range indicates high purity. |
| UV Absorption Spectral Characteristics | UV-Vis Spectrophotometry | Measures the characteristic absorption peak of MIT at 230–250 nm in ethanol or aqueous solution, used for qualitative confirmation and rapid estimation of concentration (requires calibration curve). Commonly used for quick screening. |
| Heavy Metal Detection | AAS (Atomic Absorption Spectroscopy) or ICP-MS | After sample digestion, lead, cadmium, mercury, arsenic, and other heavy metals are determined using AAS or Inductively Coupled Plasma Mass Spectrometry (ICP-MS). Meets requirements for heavy metal limits in cosmetics or food contact materials (e.g., EC 1223/2009). |
| pH Value Determination | Glass Electrode Method (pH Meter) | Measures the pH value of MIT aqueous solution (typically 0.1–1%) under constant temperature conditions using a calibrated pH meter (usually between 5.0 and 7.0). Used to assess product stability and suitability. |
| Microbial Contamination Detection (if applicable) | Pharmacopoeia Microbial Limit Test | For MIT-containing preservative formulations, microbial limit tests (e.g., aerobic bacteria count, mold and yeast count, control organisms like E. coli) are conducted according to the Chinese Pharmacopoeia or USP to ensure no microbial contamination affects test results. |
Technical Specifications of 2-Methyl-4-isothiazolin-3-one
| Test Item | Specification |
|---|---|
| Appearance | Light yellow liquid |
| Active matter | ≥10.0% |
| pH | 4~7 |
| Relative density at 20 °C | ≥1.02 |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Methyl-4-isothiazolin-3-one
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Methyl-4-isothiazolin-3-one
Packaging of 2-Methyl-4-isothiazolin-3-one
Industrial 2-Methyl-4-isothiazolin-3-one Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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