4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 26892-90-0 |
| Product name | 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of antimalarial drugs (e.g., chloroquine, hydroxychloroquine) | Cyclized with polyphosphoric acid or concentrated sulfuric acid under heating, followed by hydrolysis and esterification to produce the target drug |
| Organic Synthesis | Structural building block for constructing quinoline-based heterocyclic compounds | Serves as a starting material for 3-substituted quinoline derivatives, participating in Suzuki coupling, reduction, halogenation, and other reactions |
| Materials Science | Potential precursor for fluorescent probes or metal-ion chelating agents | Hydrolyzed to yield 4-hydroxyquinoline-3-carboxylic acid, which is further functionalized with recognition groups for preparing luminescent rare-earth coordination materials |
Manufacturing Quality Control of 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities by comparing retention times and peak areas against reference standards or threshold responses. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents using capillary GC with flame ionization detection against calibration standards. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration where iodine reacts stoichiometrically with water in a controlled anhydrous medium. |
| Heavy Metals | ICP-MS | Quantifies trace metal contaminants (e.g., Pb, Cd, Hg) by atomizing and ionizing the sample, then detecting elemental ions by mass-to-charge ratio. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection relative to calibration standards. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion of sample with sulfuric acid, followed by high-temperature incineration and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube under controlled heating rate. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles or discoloration against defined specifications under standardized lighting. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light induced by chiral molecules in solution, expressed as degrees per dm/g/mL. |
| pH of Aqueous Suspension | pH Meter | Determines hydrogen ion activity in a saturated aqueous suspension using a calibrated glass electrode system. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution by measuring angular variation in intensity of laser light scattered by dispersed particles in liquid or air. |
Technical Specifications of 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 142–146 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
Safety Information of 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
Industrial 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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