China Factory Direct
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| CAS number | 269078-73-1 |
| Product name | FMOC-HOCHA-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceutical R&D | Pharmaceutical intermediate | Used as a protected amino acid derivative in the synthesis of peptide- or protein-based therapeutics, particularly in the development of antitumor and antiviral drugs |
| Biochemistry | Reagent for solid-phase peptide synthesis (SPPS) | Applied to introduce cyclohexylalanine residues in solid-phase peptide synthesis (SPPS), with the amino group protected to enable coupling reactions |
| Organic Synthesis | Organic synthesis intermediate | Employed as a structural building block in organic synthesis to construct complex molecules, especially for targets requiring specific stereochemical configurations |
| Analytical Chemistry | Reference standard or derivatization reagent | Used as a reference standard or chiral derivatization reagent in analytical testing to support chiral analysis of amino acid compounds |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 265 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase; L-enantiomer content calculated from peak area ratio relative to racemic reference. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent; water reacts stoichiometrically with iodine and sulfur dioxide in pyridine/methanol medium. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection; quantification via external calibration curves for common solvents (e.g., DMF, THF, ethyl acetate). |
| Heavy Metals | ICP-MS | Multi-element detection after acid digestion; measures trace metal impurities (e.g., Pb, Cd, Ni, Cu) at sub-ppb levels using mass spectrometry. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., Fmoc-deprotected product, diastereomers) using gradient HPLC with UV monitoring. |
| Optical Rotation | [alpha]D Measurement | Specific rotation measured at 589 nm (Na lamp) in solution; confirms chiral integrity and batch-to-batch consistency. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically; verifies identity and crystallinity by comparison to reference material. |
| Loss on Drying | Gravimetric Heating | Mass loss measured after drying under controlled temperature and vacuum; indicates volatile content including residual solvents and moisture. |
| pH (1% w/v aqueous suspension) | pH Meter | Electrochemical measurement of hydrogen ion activity in aqueous suspension; reflects acidic/basic impurities or degradation products. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity versus angle to determine volume-based particle size distribution in dispersed powder. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms and absence of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial compendia. |
| Test Item | Specification |
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| Appearance | White solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Optical Rotation | +15.0 to +19.0° (c=1, DMF) |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.