China Factory Direct
|
|
| CAS number | 271-73-8 |
| Product name | 1H-PYRAZOLO[3,4-B]PYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing kinase inhibitors (e.g., JAK inhibitors) | Prepared via cyclization of pyrazole with pyridine derivatives; used in constructing drug molecule scaffolds |
| Agrochemicals | Agrochemical intermediate for developing novel insecticides or fungicides | Synthesized through multistep substitution and cyclization reactions; employed to build nitrogen-containing heterocyclic active ingredients |
| Chemical Research | Organic synthesis building block for constructing functionalized heterocyclic compounds | Functionalized via metal-catalyzed coupling, cycloaddition, or electrophilic substitution reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at characteristic wavelength, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities by retention time and UV response relative to reference standards. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents using gas chromatography with flame ionization detection against calibration curves. |
| Water Content | Karl Fischer Titration | Measures trace water via coulometric or volumetric titration based on iodine consumption in pyridine-methanol buffer. |
| Heavy Metals | ICP-MS | Determines trace metal contaminants (e.g., Pb, Cd, Hg) by plasma ionization and mass spectrometric detection. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Sulfate Content | Ion Chromatography | Separates and quantifies sulfate ions using anion-exchange column and conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using controlled heating and visual observation. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particulates or discoloration under standardized lighting. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Bulk Density | Tap Density Tester | Determines mass per unit volume after standardized tapping of a known powder sample in a graduated cylinder. |
| Test Item | Specification |
|---|---|
| Appearance | Light orange to yellow to green crystalline powder |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 185–189°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.