China Factory Direct
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| CAS number | 27115-49-7 |
| Product name | 3-METHYLHIPPURIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Metabolite reference standards, biomarker research | Used in LC-MS method development and validation as a key terminal metabolite reference standard for toluene metabolism pathways in humans or animals |
| Toxicological Research | Environmental and occupational exposure assessment | Quantifies toluene exposure levels via 3-methylhippuric acid concentration in urine, per ISO 16000-25 and ACGIH Biological Exposure Indices (BEI®) guidelines for biological monitoring |
| Clinical Testing | Component of in vitro diagnostic reagents | Incorporated as a calibrator or control material in urinary organic acid test kits, supporting GC-MS or LC-MS/MS detection platforms |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-DAD | Separation and identification of impurities by retention time and UV spectral matching; detection and quantification using diode array detection. |
| Residual Solvents | GC-FID | Volatile organic solvents are separated by capillary GC and quantified via flame ionization detection using external calibration standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration where iodine reacts stoichiometrically with water in a pyridine-methanol solvent system. |
| Heavy Metals | ICP-OES | Multi-element quantification of metals (e.g., Pb, Cd, Hg, As) after acid digestion, based on atomic emission intensity at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on an anion-exchange column with suppressed conductivity detection and quantification against chloride standards. |
| Sulfated Ash | Gravimetric Analysis | Sample incineration at 700-800 C followed by sulfuric acid treatment and final ash weight measurement as inorganic residue. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, using calibrated capillary tube method per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and wavelength (e.g., 589 nm). |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to calculate volume-based particle size distribution in dry or wet dispersion. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity using calibrated glass electrode and reference electrode in a 1% w/v aqueous suspension. |
| Microbial Contamination | Membrane Filtration | Quantitative recovery of viable aerobic microorganisms from sample solution by filtration, followed by incubation on soybean-casein digest agar. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 178–182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.