China Factory Direct
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| CAS number | 27126-76-7 |
| Product name | [Hydroxy(tosyloxy)iodo]benzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Used as an O-acylation reagent in the construction and modification of key drug scaffolds, including antidepressants and cardiovascular agents. |
| Organic Synthesis | Hydroxyl (alcohol/phenol) Protection | Reacted with alcohols or phenols under basic conditions to form p-toluenesulfonate esters, protecting hydroxyl functional groups from side reactions during subsequent synthetic steps. |
| Organic Synthesis | Alkylation Reagent | Employed as an alkylation reagent leveraging the excellent leaving-group ability of its p-toluenesulfonyloxy moiety, enabling nucleophilic substitution reactions with nucleophiles such as amines and thiols. |
| Materials Science | Functional Material Synthesis | Applied in the synthesis of functional polymer monomers or surfactants, introducing the p-toluenesulfonyl group to enhance material performance. |
| Analytical Chemistry | Derivatization Reagent | Used for sample derivatization prior to chromatographic analysis (e.g., HPLC, GC) to improve detection sensitivity or separation efficiency of target compounds such as alcohols. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC coupled with diode array detection and spectral comparison. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents based on retention time and response factor. |
| Heavy Metals | ICP-OES | Multi-element determination of Pb, Cd, Hg, As, and others by inductively coupled plasma optical emission spectrometry after acid digestion. |
| Moisture Content | Karl Fischer Titration | Volumetric titration with iodine-based reagent where water reacts stoichiometrically to determine trace moisture content. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying under controlled temperature and vacuum conditions per USP <731>. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with conductivity detection. |
| Sulfate Impurity | Turbidimetric Method | Reaction with barium chloride to form BaSO4 precipitate; quantification via turbidity measurement at 420 nm. |
| Residual Iodine | Redox Titration | Titration with standardized sodium thiosulfate after liberation of iodine from iodobenzene derivative under acidic conditions. |
| pH of Aqueous Suspension | pH Meter Measurement | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode per EP 2.2.3. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to determine D10, D50, D90 values per ISO 13320. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 142–146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.