China Factory Direct
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| CAS number | 272-49-1 |
| Product name | 4-Azaindole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic drug intermediate | Used to construct quinoline-based drug scaffolds |
| Pharmaceuticals | Anticancer drug synthesis | Used to synthesize microtubule inhibitor compounds |
| Pharmaceuticals | Antiviral drug synthesis | Used to synthesize HIV protease inhibitors |
| Chemicals | Organic synthesis raw material | Serves as a structural scaffold for ligand or catalyst synthesis |
| Agrochemicals | Agrochemical intermediate | Used to synthesize nitrogen-containing heterocyclic herbicides or fungicides |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity Determination | High-Performance Liquid Chromatography (HPLC) | Utilizes a reversed-phase column (e.g., C18) with a UV detector (e.g., 254 nm); quantifies the main component's purity by comparing retention time and peak area with reference standards. |
| Related Substances / Impurity Analysis | HPLC coupled with Diode Array Detector (DAD) or Mass Spectrometry (MS) | Employs gradient elution to separate potential impurities; DAD is used for spectral confirmation, and MS for structural identification, ensuring impurity levels comply with pharmacopeial or corporate standards. |
| Water Content | Karl Fischer Titration | Determines trace amounts of water in samples using either coulometric or volumetric methods, suitable for quality control of water-sensitive organic compounds. |
| Residual Solvents | Gas Chromatography (GC) | Uses headspace or direct injection with FID or MS detectors; quantifies residual organic solvents (e.g., methanol, acetonitrile) in accordance with ICH Q3C guidelines. |
| Structural Confirmation | Nuclear Magnetic Resonance (NMR), Infrared Spectroscopy (IR), Mass Spectrometry (MS) | NMR (¹H, ¹³C) provides molecular backbone information; IR confirms functional groups; MS determines molecular weight and fragmentation patterns, collectively verifying the chemical structure. |
| Melting Point Determination | Capillary Melting Point Apparatus | Measures the temperature range over which a substance transitions from solid to liquid, serving as a physical constant for auxiliary identification and purity assessment. |
| Appearance and Characteristics | Visual Inspection, Microscopic Observation | Examines color, crystal form, particle morphology, and other physical attributes to ensure compliance with standard descriptions (e.g., white to off-white crystalline powder). |
| Drying Loss | Oven Drying Method | Dries the sample to constant weight at a specified temperature (e.g., 105°C) and calculates the percentage of mass loss, reflecting volatile components or adsorbed water content. |
| Heavy Metal Content | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | After sample digestion, detects elemental residues such as lead, cadmium, mercury, and arsenic to ensure compliance with ICH Q3D or pharmacopeial limits. |
| pH Value (if applicable to solutions) | pH Meter Measurement | Prepares a specified concentration aqueous solution of the sample and measures pH using a calibrated pH meter to evaluate acidity/basicity effects on stability or formulation. |
| Test Item | Specification |
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| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 124-128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.