1H-PYRAZOLO[4,3-B]PYRIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 272-52-6 |
| Product name | 1H-PYRAZOLO[4,3-B]PYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1H-PYRAZOLO[4,3-B]PYRIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1H-PYRAZOLO[4,3-B]PYRIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1H-PYRAZOLO[4,3-B]PYRIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as an organic synthesis intermediate for constructing nitrogen-containing heterocyclic drug molecules | Prepared via selective N-alkylation or cyclization of indazole derivatives |
| Pharmaceutical Manufacturing | Used to synthesize scaffold structures for kinase inhibitors, antitumor agents, and antiviral compounds | Synthesized through a multi-step sequence involving cyclization, reduction, and rearrangement of o-nitrophenylhydrazine with malonate esters |
| Chemical Research | Employed as a ligand or functionalization unit in metal–organic framework (MOF) and catalytic system studies | Constructed via multicomponent condensation or transition metal-catalyzed C–H activation reactions |
Manufacturing Quality Control of 1H-PYRAZOLO[4,3-B]PYRIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification via retention time matching and threshold-based reporting. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine-based reagent, based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Quantifies trace heavy metals (e.g., Pb, Cd, Hg) after acid digestion using inductively coupled plasma mass spectrometry for multi-element sensitivity. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled charring and sulfuric acid treatment, followed by high-temperature ignition and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus under controlled heating rate. |
| Loss on Drying | Thermogravimetric Analysis | Measures mass loss upon heating under defined conditions (e.g., 105 C, 2 h) to assess volatile content and residual moisture. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in suspension using Mie scattering theory and laser diffraction optics. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures hydrogen ion activity in a standardized aqueous slurry (e.g., 1% w/v) using calibrated pH electrode. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration after incubation. |
Technical Specifications of 1H-PYRAZOLO[4,3-B]PYRIDINE
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 148–152 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1H-PYRAZOLO[4,3-B]PYRIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1H-PYRAZOLO[4,3-B]PYRIDINE
Packaging of 1H-PYRAZOLO[4,3-B]PYRIDINE
Industrial 1H-PYRAZOLO[4,3-B]PYRIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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