China Factory Direct
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| CAS number | 272-97-9 |
| Product name | 5-AZABENZIMIDAZOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used in the synthesis of antihistamine drugs, such as fexofenadine | Reacted with corresponding haloalkanes to form the target compound |
| Chemical Manufacturing | Serves as an intermediate in organic synthesis | Undergoes a series of chemical transformations, including but not limited to substitution and addition reactions |
| Research | Employed as a tool molecule to investigate biological activity and potential applications | Tested against specific biological targets through designed experiments |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Characteristics | Visual Inspection / Microscopic Observation | Observe the sample's color, crystal form, particle state, and presence of foreign particles using naked eye or optical microscope to determine compliance with specified standards (e.g., white to off-white crystalline powder). |
| Identification Test | Infrared Spectroscopy (IR) Proton Nuclear Magnetic Resonance (¹H NMR) Mass Spectrometry (MS) |
- IR: Measure the infrared absorption spectrum of the sample and compare characteristic absorption peaks (e.g., C=N, N–H functional groups) with reference spectra; - ¹H NMR: Analyze chemical shifts and coupling constants of hydrogen atoms to confirm molecular structure; - MS: Determine molecular ion peak and fragment ions to verify molecular weight and structural features. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with an appropriate mobile phase (e.g., methanol-water or acetonitrile-buffer salt system) for gradient or isocratic elution, detect using UV detector (typically at ~254 nm), and calculate main component content via external standard method or area normalization method to ensure purity meets requirements (usually ≥98.0%). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Similar conditions as for content determination, but optimized for resolution to detect and quantify potential impurities (e.g., starting material residues, by-products, degradation products). Use self-control method or main component self-control method with correction factors to control limits for individual and total impurities. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection with polar or non-polar capillary columns and FID detection. Follow ICH Q3C guidelines to detect organic solvents (e.g., methanol, dichloromethane, DMF) potentially residual from synthesis or purification processes, ensuring they remain within acceptable safety limits. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight, then calculate the percentage of mass loss to assess moisture and volatile substance content. |
| Residue on Ignition | High-Temperature Ashing Method | Char the sample, then ignite at 700–800°C in a muffle furnace until constant weight. Weigh the resulting inorganic residue to control total inorganic impurities (typically ≤0.1%). |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After acid digestion of the sample, use AAS or ICP-MS to determine levels of heavy metals such as lead, cadmium, mercury, and arsenic, ensuring compliance with pharmacopoeial or ICH Q3D elemental impurity limits. |
| pH Value (if applicable) | pH Meter Measurement | Dissolve the sample in water at a defined concentration (e.g., 1% w/v), then measure pH using a calibrated pH meter to ensure it falls within the specified range (applicable when the compound is in salt form or requires buffering). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 128-132°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.