China Factory Direct
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| CAS number | 27298-98-2 |
| Product name | (S)-(-)-1-(P-TOLYL)ETHYLAMINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral intermediate in the synthesis of antidepressants (e.g., duloxetine) and anti-Parkinson’s drugs | Synthesized from corresponding ketone precursors via asymmetric reduction or chiral resolution |
| Pesticides | Used to synthesize chiral intermediates for novel insecticides or fungicides | Prepared using chiral catalyst–mediated hydrogenation or enzymatic resolution |
| Chemical Reagents | Employed as chiral ligands or auxiliaries in asymmetric organic synthesis | Obtained from commercially available racemates via chiral chromatographic separation or chemical resolution |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard under validated chromatographic conditions. |
| Enantiomeric Excess (ee) | Chiral Gas Chromatography (cGC) or Chiral HPLC | Separation of (S)- and (R)-enantiomers on a chiral stationary phase; ee calculated from relative peak areas. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration quantifying water via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile organic solvents quantified by equilibrium partitioning into headspace followed by GC-FID analysis. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Element-specific detection after acid digestion and nebulization; provides ultra-trace multi-element quantification. |
| Chloride Impurity | Ion Chromatography (IC) with conductivity detection | Anion separation on ion-exchange column; chloride quantified by conductivity response relative to calibration standards. |
| Appearance and Color | Visual Inspection and APHA Color Scale | Comparison of sample solution (in specified solvent, e.g., methanol) against standardized platinum-cobalt color standards. |
| Specific Optical Rotation | [α]D | Measurement of plane-polarized light rotation at 589 nm (Na-D line) using a calibrated polarimeter; confirms chiral integrity and concentration. |
| Acid-Base Impurities (e.g., free amine, residual acid) | Non-aqueous Acid-Base Titration (with perchloric acid in glacial acetic acid) | Potentiometric or visual endpoint titration to quantify total basic nitrogen content relative to primary amine functionality. |
| Residual Catalyst (e.g., Pd, Rh) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Quantification of metal residues after microwave-assisted acid digestion via element-specific atomic emission intensities. |
| Related Substances | Reverse-Phase High-Performance Liquid Chromatography (RP-HPLC) with UV detection | Separation and quantification of structurally related impurities (e.g., ketone precursor, N-oxides, dimers) using gradient elution and UV absorbance at 210–254 nm. |
| pH (of aqueous solution) | pH Meter Measurement | Electrochemical measurement of hydrogen ion activity in a defined aqueous solution (e.g., 10% w/v in water) using calibrated pH electrode. |
| Density | Digital Density Meter (Oscillating U-tube principle) | Determination of mass per unit volume at specified temperature (e.g., 20 °C) via resonant frequency shift of a vibrating U-shaped tube filled with sample. |
| Refractive Index | Digital Refractometer | Measurement of light bending angle at air-sample interface at specified wavelength (e.g., 589 nm) and temperature (e.g., 20 °C). |
| Test Item | Specification |
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| Appearance | Colorless liquid |
| Purity | >=98.0% (HPLC), >=98% ee |
| Optical Rotation | -32.4 to -25.0 deg (c=1, in methanol) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.525–1.535 |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.