China Factory Direct
|
|
| CAS number | 2737-20-4 |
| Product name | 4-bromo-3-(hydroxymethyl)phenol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of antifungal agents (e.g., clotrimazole derivatives) | Undergoes nucleophilic substitution with imidazole rings to form C–N bonds |
| Agrochemical Intermediates | Used in the preparation of novel fungicides and plant growth regulators | Bromination followed by hydroxyl protection, coupling, and subsequent deprotection to introduce active functional groups |
| Organic Synthesis | Multi-functional building block for constructing aromatic heterocyclic systems via Suzuki coupling, Heck reactions, etc. | Participates in palladium-catalyzed cross-coupling reactions with arylboronic acids or alkenes |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase chromatography with UV detection at 220-280 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Separates and quantifies structurally related impurities (e.g., brominated isomers, oxidation/debromination products) using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Identifies and quantifies residual solvents (e.g., methanol, ethyl acetate, toluene) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine generated electrochemically in a methanol-based reagent. |
| Heavy Metals | ICP-OES | Measures total heavy metal content (Pb, Cd, Hg, As, Ni) after acid digestion by atomic emission spectroscopy at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography | Quantifies chloride ion using suppressed conductivity detection after separation on an anion-exchange column with carbonate/bicarbonate eluent. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after charring at 600-750 C and weighing the cooled crucible. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using controlled heating and visual observation of meniscus collapse. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light passing through a solution in a defined pathlength cell to assess chiral purity. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode pH probe. |
| Appearance | Visual Inspection | Evaluates physical state, color, and presence of foreign particles or phase separation under standardized white light and against reference standards. |
| Bulk Density | Tap Density Tester | Determines mass per unit volume after controlled tapping of a known mass in a graduated cylinder according to USP <616>. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 112–116°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.