China Factory Direct
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| CAS number | 27407-11-0 |
| Product name | 3-Bromo-4-fluorophenol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical Intermediates | Used in the synthesis of antimicrobial, anti-inflammatory, or anticancer drug molecules | Serves as a bromo- or fluoro-substituted aromatic ring precursor for constructing complex molecular scaffolds via Suzuki coupling, nucleophilic substitution, and related reactions |
| Agrochemical Intermediates | Synthesis of herbicidal or insecticidal active ingredients containing fluorinated phenol structures | Introduces target functionalities into molecules via halogen exchange or functional group transformation to enhance biological activity and metabolic stability |
| Organic Synthesis Reagents | General building block for constructing polysubstituted benzene ring systems | Enables cross-coupling reactions leveraging the high reactivity of the bromine atom, while the fluorine atom modulates electronic effects and steric hindrance |
| Materials Science | Used to prepare fluorinated liquid crystal monomers or precursors for optoelectronic materials | Acts as a rigid benzene ring unit in condensation or grafting reactions to improve thermal stability and dielectric properties of materials |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-280 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, toluene) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent; water reacts stoichiometrically with iodine and sulfur dioxide in pyridine/methanol medium. |
| Acidity (as HBr) | Acid-Base Titration | Titration with standardized NaOH solution using phenolphthalein or potentiometric endpoint detection to measure acidic impurities. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification after acid digestion; detection based on characteristic atomic emission wavelengths in inductively coupled plasma. |
| Chloride Impurity | Ion Chromatography | Separation of anions on ion-exchange column with suppressed conductivity detection; chloride quantified against calibration curve. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as solid-to-liquid phase change under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of color and physical state (crystalline solid) against standard white background under controlled lighting. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying sample at specified temperature (e.g., 105 C) for fixed duration under vacuum or air. |
| Residue on Ignition | Sulfated Ash Test | Mass of inorganic residue remaining after high-temperature incineration (600-750 C) following sulfuric acid treatment. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution; indicates chiral purity and absence of racemization. |
| Test Item | Specification |
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| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 42–46°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.