Ethyl L-leucinate hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2743-40-0 |
| Product name | Ethyl L-leucinate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Ethyl L-leucinate hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl L-leucinate hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Ethyl L-leucinate hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of peptide-based drugs | Used as a chiral building block or protected amino acid unit in solid-phase or solution-phase peptide synthesis |
| Chemical Research | Organic synthesis reagent | Applied in constructing complex molecular frameworks, such as antibiotics and enzyme inhibitors |
| Biotechnology | Development of drug delivery systems | Employed in esterification modifications to enhance drug lipophilicity and cellular permeability |
| Pharmaceutical Manufacturing | Prodrug design | Leveraged for its metabolic properties as a leucine-based prodrug moiety to improve the bioavailability of active pharmaceutical ingredients |
Manufacturing Quality Control of Ethyl L-leucinate hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration | Quantifies L-leucine ethyl ester hydrochloride by titration with standardized NaOH using an indicator or potentiometric endpoint detection. |
| Water Content | Karl Fischer Titration | Measures water content via coulometric or volumetric reaction between water and iodine generated in situ from KF reagent. |
| Specific Optical Rotation | Polarimetry | Determines enantiomeric purity by measuring the angle of rotation of plane-polarized light in a solution at specified concentration and wavelength. |
| Residual Solvents | Gas Chromatography (GC-FID) | Separates and quantifies volatile organic solvents (e.g., ethanol, ethyl acetate) using flame ionization detection. |
| Heavy Metals | ICP-OES | Quantifies trace metal impurities (e.g., Pb, Cd, Ni) after acid digestion by measuring element-specific atomic emission intensities. |
| Chloride Content | Potentiometric Titration | Determines chloride ion concentration using silver nitrate titrant and a silver/silver chloride electrode for endpoint detection. |
| Related Substances | HPLC-UV | Separates and quantifies structurally related impurities (e.g., L-leucine, diethyl ester, hydrolysis products) using reversed-phase chromatography and UV detection. |
| pH (1% aqueous solution) | pH Meter Measurement | Measures hydrogen ion activity in a standardized aqueous solution using calibrated glass electrode system. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against established reference standards under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method per pharmacopeial guidelines. |
| Loss on Drying | Gravimetric Analysis | Measures volatile matter loss by weight difference before and after drying at specified temperature and time under vacuum or air. |
| Microbial Contamination | Membrane Filtration | Detects viable aerobic microorganisms by filtration, membrane transfer to nutrient agar, and colony enumeration after incubation. |
Technical Specifications of Ethyl L-leucinate hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Optical Rotation | +18.0 to +20.0° (c=1, in 6N HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Ethyl L-leucinate hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Ethyl L-leucinate hydrochloride
Safety Information of Ethyl L-leucinate hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Ethyl L-leucinate hydrochloride
Industrial Ethyl L-leucinate hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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