4,4'-Difluorobenzhydrylpiperazine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 27469-60-9 |
| Product name | 4,4'-Difluorobenzhydrylpiperazine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4,4'-Difluorobenzhydrylpiperazine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4,4'-Difluorobenzhydrylpiperazine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4,4'-Difluorobenzhydrylpiperazine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a synthetic intermediate in drug manufacturing, particularly for psychotropic agents and antidepressants | Employed in organic synthesis as a key building block to introduce structural units via substitution, condensation, and related reactions |
| Research | Used as a chemical reagent in organic chemistry, medicinal chemistry research, and new drug development | Applied under laboratory conditions for synthesizing complex molecules, structure–activity relationship studies, or pharmacological testing |
| Chemical Manufacturing | Used as a precursor in the synthesis of specialty functional materials or fine chemicals | Acting as a modifying monomer or crosslinker in polymerization processes or functional molecular design |
Manufacturing Quality Control of 4,4'-Difluorobenzhydrylpiperazine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~220–230 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities (e.g., mono-fluoro analogs, des-fluoro compound, synthesis intermediates) using gradient elution and UV detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace gas chromatography with flame ionization detection (or mass spectrometry) to quantify residual solvents (e.g., dichloromethane, methanol, toluene) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (e.g., Pb, Cd, Hg, As) after acid digestion, with detection limits compliant with ICH Q3D. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by high-temperature incineration followed by precise weighing of the residue. |
| Optical Rotation | [α]D Measurement | Specific rotation measurement at 20 °C using sodium D-line (589 nm) to confirm chiral integrity and absence of racemization. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating rate, verifying identity and crystallinity. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Quantification of chloride ions either via suppressed conductivity detection in IC or argentometric titration with silver nitrate endpoint detection. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or dispersed powder sample to determine volumetric particle size distribution based on light scattering principles. |
| Microbial Limits | Membrane Filtration & Colony Counting | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
Technical Specifications of 4,4'-Difluorobenzhydrylpiperazine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 128–132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4,4'-Difluorobenzhydrylpiperazine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4,4'-Difluorobenzhydrylpiperazine
Safety Information of 4,4'-Difluorobenzhydrylpiperazine
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 4,4'-Difluorobenzhydrylpiperazine
Industrial 4,4'-Difluorobenzhydrylpiperazine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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