L-Leucine tert-butyl ester hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2748-02-9 |
| Product name | L-Leucine tert-butyl ester hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for L-Leucine tert-butyl ester hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk L-Leucine tert-butyl ester hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of L-Leucine tert-butyl ester hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a synthetic intermediate in the production of antibiotics, antiviral agents, and peptide-based drugs | Employed as a raw material or building block in organic synthesis to introduce the leucine tert-butyl ester moiety via condensation, acylation, and related reactions |
| Biochemistry | Applied as a protected amino acid monomer in solid-phase peptide synthesis to prevent undesired side reactions | Integrated into peptide chain assembly on automated synthesizers via stepwise coupling; the hydrochloride salt form improves stability and solubility |
| Research | Utilized as a biochemical reagent in enzymatic reaction studies or cell culture experiments | Prepared as aqueous solutions under laboratory conditions for in vitro enzyme kinetics assays or as a medium additive |
Manufacturing Quality Control of L-Leucine tert-butyl ester hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 200-220 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of L- and D-enantiomers on a chiral stationary phase, with UV detection to determine enantiomeric excess. |
| Loss on Drying | Gravimetric (Thermogravimetric) | Mass loss measured after drying at 105 C for 2 hours under controlled atmospheric conditions. |
| Residual Solvents | GC-FID | Quantitative analysis of volatile organic solvents (e.g., tert-butanol, ethyl acetate) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and plasma excitation. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to detect endpoint based on AgCl precipitation potential change. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Direct measurement of pH in a 1% w/v aqueous suspension using a calibrated glass electrode pH meter. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a standardized solution to confirm chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid-to-liquid transition occurs, indicating purity and identity. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., L-leucine, di-tert-butyl derivative) using gradient HPLC. |
| Water Content | Karl Fischer Coulometric Titration | Electrochemical titration with iodine generated in situ to quantify trace water content in the sample. |
| Residue on Ignition | Gravimetric (Sulfated Ash) | Mass of non-volatile inorganic residue remaining after high-temperature ignition (700-800 C) following sulfuric acid treatment. |
Technical Specifications of L-Leucine tert-butyl ester hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 132-136°C |
| Optical Rotation | +18.0 to +21.0 deg (c=1, in 6N HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of L-Leucine tert-butyl ester hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of L-Leucine tert-butyl ester hydrochloride
Safety Information of L-Leucine tert-butyl ester hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of L-Leucine tert-butyl ester hydrochloride
Industrial L-Leucine tert-butyl ester hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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