China Factory Direct
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| CAS number | 27607-77-8 |
| Product name | Trimethylsilyl trifluoromethanesulfonate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate in drug synthesis; used for hydroxyl group protection/deprotection and ether formation | Catalyzed organic synthesis |
| Pharmaceutical Industry | Coupling reactions in the synthesis of nucleoside and carbohydrate compounds (e.g., deoxynucleosides) | Glycosylation |
| Agrochemical Industry | Synthesis and modification of agrochemicals and fine chemicals | Catalyzed/condensation reactions |
| Organic Synthesis | Highly effective silylation reagent for introducing the trimethylsilyl (TMS) protecting group | Silylation |
| Organic Synthesis | Catalyst or initiator in certain rearrangement reactions (e.g., pinacol rearrangement) | Rearrangement |
| Materials Science | Synthesis and modification of organosilicon chemicals | Polymer modification |
| Test Item | Common Testing Method | Method Overview |
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| Purity (Content) | Gas Chromatography (GC) | Utilizes internal or external standard methods; the peak area of the target component is measured using a gas chromatograph to calculate purity. Capillary columns (e.g., DB-5MS) are commonly used with nitrogen as carrier gas and programmed temperature ramping, making it suitable for volatile organic compound analysis. |
| Moisture Content | Karl Fischer Titration | Based on the quantitative reaction between Karl Fischer reagent and water in the sample, with moisture content determined by titration endpoint detection. Suitable for trace moisture analysis and critical for controlling moisture levels in TMSOTf. |
| Acidity (Free Acid) | Acid-Base Titration (Non-aqueous Titration) | Performed in anhydrous solvents (e.g., glacial acetic acid), using standardized perchloric acid solution to titrate acidic impurities, with phenolphthalein or crystal violet as indicators, to assess the level of acidic impurities. |
| Impurity Analysis (Organic Impurities) | Gas Chromatography-Mass Spectrometry (GC-MS) | Combines the separation capability of GC with the qualitative identification power of MS, effectively identifying and quantifying trace organic impurities such as unreacted raw materials and by-products. |
| Metal Impurities (e.g., Sodium, Iron, Nickel, etc.) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After acid digestion of the sample, ICP-MS is used for elemental analysis, capable of detecting metal impurities at ppb levels to ensure compliance with high-purity chemical requirements. |
| Silicon Content (or Silane-related Impurities) | Atomic Absorption Spectroscopy (AAS) / ICP-OES | Used to determine total silicon or specific silicon compound content, assisting in assessing the level of silicate-type impurities. |
| Thermal Stability / Decomposition Products | Thermogravimetric Analysis (TGA) + Gas Chromatography-Mass Spectrometry (GC-MS) | TGA monitors weight loss behavior under heat, while GC-MS analyzes evolved gases to identify potentially harmful decomposition products at elevated temperatures. |
| Density / Relative Density | Density Meter Method (U-tube Density Meter) | Measures the sample density at 20°C using a digital density meter, serving as a physical property parameter for process control and batch-to-batch consistency verification. |
| Appearance and Color | Visual Inspection / Spectrophotometry | Checks whether the liquid is clear and transparent, colorless or pale yellow; UV-Vis spectrophotometry can be used to detect abnormal absorbance at 254 nm or 365 nm, indicating the presence of impurities or degradation products. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow clear liquid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.395–1.405 |
| Relative Density (20°C/25°C) | 1.27–1.29 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.