China Factory Direct
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| CAS number | 2762-32-5 |
| Product name | 2-Piperazinecarboxylic acid dihydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antiviral drugs (e.g., abacavir) | Used to construct heterocyclic structures via organic synthesis reactions, including acylation and alkylation |
| Pharmaceuticals | Used in the preparation of HIV reverse transcriptase inhibitors | Applied as a piperazine ring incorporation unit in multistep synthesis |
| Chemical Reagents | Organic synthesis building block for constructing piperazine-containing molecules | Participates in condensation and substitution reactions for drug lead compound library construction |
| Agrochemicals | Potential intermediate in the synthesis of biologically active pesticides | Applied as a nitrogen-containing heterocyclic precursor in heterocycle synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Piperazine-2-carboxylic acid hydrochloride) | Acid-base titration with NaOH | Quantifies active ingredient by neutralizing HCl salt and free acid groups using standardized sodium hydroxide solution. |
| Water Content | Karl Fischer titration | Measures water via iodine-sulfur dioxide reaction in anhydrous methanol medium with coulometric or volumetric detection. |
| Residue on Ignition | Gravimetric analysis | Determines inorganic ash content by high-temperature incineration followed by precise weighing of residual solids. |
| Heavy Metals | ICP-OES | Quantifies trace metal impurities (e.g., Pb, Cd, Ni) by plasma excitation and elemental emission spectroscopy. |
| Chloride Impurity | Potentiometric titration with AgNO3 | Detects chloride ions by silver nitrate titration monitored with silver indicator electrode. |
| Related Substances | HPLC with UV detection | Separates and quantifies structurally similar impurities using reversed-phase chromatography and UV absorbance at 210 nm. |
| Optical Rotation | Polarimetry | Measures specific rotation using plane-polarized light to confirm chiral purity and identity. |
| pH of Aqueous Solution | Potentiometric pH measurement | Determines acidity/basicity of a defined aqueous suspension using calibrated pH electrode. |
| Loss on Drying | Thermogravimetric analysis (TGA) or oven drying | Quantifies volatile content by mass loss after controlled heating under specified time/temperature conditions. |
| Particle Size Distribution | Laser diffraction | Analyzes size distribution of solid particles in suspension based on angular scattering intensity of laser beam. |
| Microbial Limits | Membrane filtration and colony counting | Detects and enumerates aerobic microorganisms using sterile filtration, culture on agar media, and CFU enumeration. |
| Organic Volatile Impurities | GC-FID | Identifies and quantifies residual solvents (e.g., methanol, acetone) by gas chromatographic separation and flame ionization detection. |
| Test Item | Specification |
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| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 210-215°C (decomposes) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.