China Factory Direct
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| CAS number | 27665-39-0 |
| Product name | 1,4-Butane-disulfonate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Electroplating | Added to copper electroplating baths to improve deposit uniformity and brightness | Added to acidic sulfate copper plating baths at typical concentrations of 1–10 mg/L; acts synergistically with chloride ions to refine grain structure |
| Organic Synthesis | Used as a multifunctional sulfonating agent and crosslinker | Participates in condensation reactions to prepare sulfonic acid-functionalized polymers; undergoes substitution or condensation polymerization with diols, diamines, and other bifunctional compounds under alkaline conditions |
| Water Treatment | Component of scale and dispersion inhibitors to suppress calcium carbonate and calcium sulfate scaling | Formulated into multi-component copolymer systems (e.g., acrylic acid/sulfonic acid copolymers); functions via combined chelation and crystal lattice distortion mechanisms |
| Pharmaceutical Intermediates | Key side-chain precursor in the synthesis of the antithrombotic drug tirofiban | Introduced as a sulfonic acid-containing butanediamine derivative via multi-step reactions including esterification, amidation, and chiral resolution |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Take an appropriate amount of sample and place it on a white background. Observe its color, state, and presence of visible impurities under natural light or standard illumination. It should be a white crystalline powder or a colorless to slightly yellow solid. |
| Identification | Infrared Spectroscopy (IR) Nuclear Magnetic Resonance (¹H NMR) |
Compare the characteristic absorption peaks of the sample with the standard spectrum using IR; or determine the chemical shift and coupling constants of hydrogen atoms by ¹H NMR to confirm whether the molecular structure matches that of 1,4-butanedisulfonic acid. |
| Content Determination | Acid-Base Titration High-Performance Liquid Chromatography (HPLC) |
Acid-Base Titration: Titrate the total acidity of the sample with a standard sodium hydroxide solution, using phenolphthalein as an indicator, and calculate the content of the main component. HPLC: Use a reversed-phase C18 column, with a phosphate buffer-methanol mobile phase, and detect at 210 nm with a UV detector, using an external standard method for quantification. |
| pH Value | pH Meter Method | Prepare a solution of a certain concentration (e.g., 1% w/v) and measure its pH value using a calibrated pH meter. The value should be within the specified range (usually 1.0–3.0). |
| Drying Loss | Thermogravimetric Analysis (TGA) or Drying to Constant Weight | Dry the sample at 105°C until constant weight is achieved, and calculate the percentage of mass loss to evaluate the moisture and volatile substance content. |
| Residue on Ignition | Ignition Method (as per Pharmacopoeia General Rules) | Ignite the sample at high temperature (usually 700–800°C), then weigh the residual inorganic matter to assess the total amount of inorganic impurities. |
| Heavy Metals | Sodium Sulfacetamide Method (Colorimetry) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Sodium Sulfacetamide Method: Generate a colored precipitate by reacting with sodium sulfacetamide under acidic conditions, and compare it with a standard lead solution; ICP-MS: Determine the content of specific heavy metal elements such as lead, arsenic, cadmium, and mercury with high sensitivity. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use a gradient elution HPLC system to separate and detect possible synthetic by-products or degradation impurities (such as monosulfonic acid derivatives or unreacted raw materials). Limit control is performed using area normalization or the main component self-control method with correction factors. |
| Moisture | Karl Fischer Titration | Quantitatively react the sample's water with Karl Fischer reagent, and accurately determine the moisture content using coulometry or volumetry. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow clear liquid |
| Purity | 98.0–99.5% (anhydrous basis) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 145–149°C |
| Acid Value (mg KOH/g) | 680–720 mg KOH/g |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.