China Factory Direct
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| CAS number | 27960-59-4 |
| Product name | TRANS-4-AMINO-CYCLOHEXANE CARBOXYLIC ACID HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate for the synthesis of the antiepileptic drug lacosamide | Used in chiral resolution or asymmetric synthesis of lacosamide, followed by amidation, reduction, and related steps |
| Pharmaceuticals | Development of novel neuroprotective agents and sodium channel modulators | Serves as a cyclohexane-based structural scaffold for medicinal chemistry design and structure–activity relationship (SAR) studies |
| Chemicals | High-purity chiral building block for synthesizing other fine chemicals containing the cyclohexylamine motif | Purified via recrystallization, chiral chromatography, or similar methods, then employed in multistep organic synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration | Quantifies active ingredient by titration with standardized NaOH solution using an indicator or potentiometric endpoint detection. |
| Water Content | Karl Fischer Titration | Measures water content based on stoichiometric reaction between water and iodine in a methanol-based reagent. |
| Residual Solvents | Gas Chromatography (GC) | Separates and quantifies volatile organic solvents using a capillary column and flame ionization detector. |
| Heavy Metals | ICP-OES | Determines total heavy metal content (e.g., Pb, Cd, Hg, As) after acid digestion via atomic emission spectroscopy. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions using an anion-exchange column and conductivity detection. |
| Related Substances | HPLC with UV Detection | Separates and quantifies structurally related impurities using reversed-phase chromatography and UV absorbance at 210 nm. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light to confirm chiral purity and identity of the trans-isomer. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines acidity of a defined aqueous solution using calibrated glass electrode and reference electrode. |
| Residue on Ignition | Gravimetric Analysis | Quantifies non-volatile inorganic residue after high-temperature ashing and weighing. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution by analyzing angular variation in laser light scattering pattern. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using controlled heating and visual observation. |
| Microbial Limits | Membrane Filtration and Culture | Detects and enumerates aerobic microorganisms and specified pathogens using selective media and incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 240-245 °C (decomposes) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15.0 to -18.0 ° (c=1, H2O) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.