1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 28049-61-8 |
| Product name | 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antipsychotic agents (e.g., olanzapine) | Amination or subsequent cyclization of 1-(4-chlorophenyl)cyclobutane-1-carbonitrile to construct imidazopyridine or thienopyridine core structures |
Manufacturing Quality Control of 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at characteristic wavelength, calibrated against certified reference standard. |
| Related Substances | HPLC-DAD or HPLC-MS | Separation and identification of impurities by retention time and spectral/fragmentation data relative to main peak. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generation in pyridine-methanol medium; endpoint detected amperometrically. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion by measuring atomic emission intensities at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on ion-exchange column with suppressed conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Mass loss measurement after high-temperature ashing to determine inorganic residue content. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually as solid-to-liquid phase change under controlled heating rate. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through solution, indicating chiral purity. |
| Particle Size Distribution | Laser Diffraction | Analysis of light scattering pattern from dispersed particles to calculate size distribution by Mie theory. |
| Bulk Density | USP <616> Tap Density Method | Determination of mass per unit volume after standardized tapping of a powder sample in a graduated cylinder. |
| Microbial Limits | Membrane Filtration and Plate Count | Viable microorganism enumeration via filtration, membrane transfer to selective media, and colony formation counting. |
Technical Specifications of 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Melting Point | 45–49 °C |
| Odor | Characteristic, mild |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile
Safety Information of 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile
Industrial 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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