Piperidin-3-one-hydrochloride Hydrate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2828446-66-6 |
| Product name | Piperidin-3-one-hydrochloride Hydrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Piperidin-3-one-hydrochloride Hydrate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Piperidin-3-one-hydrochloride Hydrate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Piperidin-3-one-hydrochloride Hydrate
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceutical R&D | Pharmaceutical intermediates | Used as a key intermediate in the synthesis of multiple central nervous system drugs |
| Pharmaceutical R&D | Analgesic synthesis | Applied in structural modification and optimization of piperidine-based analgesics |
| Pharmaceutical R&D | Psychotropic drug development | Employed in molecular construction of antidepressants and anxiolytics |
| Chemical synthesis | Heterocyclic compound synthesis | Used as a nucleophile in organic synthesis reactions |
| Pesticide R&D | Pesticide active ingredient synthesis | Applied in the preparation of biologically active pesticide derivatives |
| Laboratory research | Organic synthesis reagent | Used in organic synthesis experiments at universities and research institutions |
Manufacturing Quality Control of Piperidin-3-one-hydrochloride Hydrate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Piperidin-3-one Hydrochloride Hydrate Content) | HPLC with UV detection | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV absorbance at ~210 nm. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation proportional to water content in the sample. |
| Residual Solvents (e.g., Ethanol, Acetone, THF) | Headspace Gas Chromatography (HS-GC) with FID | Volatile solvents are vaporized in sealed vials, separated on a capillary column, and quantified by flame ionization detection. |
| Heavy Metals (Pb, Cd, Hg, As, Cr) | ICP-MS | Multi-element quantification of trace metals after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppq sensitivity. |
| Chloride Impurity | Potentiometric Titration with AgNO₃ | Direct titration with silver nitrate; endpoint detected by potential change due to AgCl precipitation. |
| Related Substances (Impurities & Degradants) | HPLC with UV detection | Separation and quantification of structurally related impurities using gradient reversed-phase chromatography and UV detection. |
| pH of Aqueous Solution (1% w/v) | pH Potentiometry | Measurement of hydrogen ion activity in a standardized aqueous suspension using a calibrated glass electrode system. |
| Appearance (Color & Clarity) | Visual Inspection against Standard Solutions | Comparison of sample solution color and clarity with pharmacopeial standards (e.g., USP <631>) under controlled lighting. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Incineration of sample to convert organic matter to volatile products; remaining inorganic residue is weighed after sulfuric acid treatment. |
| Microbial Contamination (Total Aerobic Count, Yeast/Mold) | Membrane Filtration with TSA/SDA Culture | Sample filtration followed by incubation on tryptic soy agar or sabouraud dextrose agar; colony enumeration per pharmacopeial limits. |
Technical Specifications of Piperidin-3-one-hydrochloride Hydrate
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 142-146°C |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Piperidin-3-one-hydrochloride Hydrate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Piperidin-3-one-hydrochloride Hydrate
Packaging of Piperidin-3-one-hydrochloride Hydrate
Industrial Piperidin-3-one-hydrochloride Hydrate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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