3-bromo-2,6-difluorobenzoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 28314-81-0 |
| Product name | 3-bromo-2,6-difluorobenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-bromo-2,6-difluorobenzoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-bromo-2,6-difluorobenzoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-bromo-2,6-difluorobenzoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediate | Serves as a key scaffold for constructing fluorinated aromatic ring systems in the synthesis and development of novel drug molecules. |
| Agrochemicals | Agrochemical Intermediate | Used in coupling reactions to synthesize novel fluorinated fungicides or herbicides, leveraging its halogen-substituted structure. |
| Organic Synthesis | Specialty Organic Synthon | Employed in cross-coupling reactions—including Suzuki and Buchwald-Hartwig couplings—to construct complex biaryl or arylamine compounds. |
| Organic Synthesis | Functional Group Transformation Substrate | Converted via hydrolysis, reduction, or esterification into 3-bromo-2,6-difluorobenzoic acid derivatives (e.g., acid chlorides, amides) for downstream synthesis. |
Manufacturing Quality Control of 3-bromo-2,6-difluorobenzoic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main compound using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Identifies and quantifies impurities (e.g., bromination by-products, hydrolysis products) using gradient HPLC and UV detection. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., toluene, THF, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based reagent and electrochemical endpoint detection. |
| Heavy Metals | ICP-OES | Measures total elemental metals (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Quantifies chloride ions using suppressed conductivity detection after separation on anion-exchange column. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light and against standard references. |
| Acid Value | Acid-Base Titration | Determines carboxylic acid content by titration with standardized NaOH solution using phenolphthalein indicator. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension using Mie scattering theory and laser diffraction optics. |
| Bulk Density | Tap Density Measurement | Determines mass per unit volume of powder after specified tapping cycles using standardized cylinder and tap apparatus. |
Technical Specifications of 3-bromo-2,6-difluorobenzoic acid
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 142–146 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-bromo-2,6-difluorobenzoic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-bromo-2,6-difluorobenzoic acid
Safety Information of 3-bromo-2,6-difluorobenzoic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-bromo-2,6-difluorobenzoic acid
Industrial 3-bromo-2,6-difluorobenzoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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