China Factory Direct
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| CAS number | 28314-83-2 |
| Product name | 5-BroMo-2,4-difluoro-benzoic Acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthesis of antiviral drug intermediates | Used as a key intermediate in coupling reactions of fluorinated aromatic compounds to construct active pharmaceutical ingredients |
| Agrochemicals | Synthesis of plant growth regulators and fungicides | Applied as a building block for fluorinated agrochemical molecules, introducing functional groups via acylation or halogen substitution |
| Organic Synthesis | Precurser for liquid crystal materials and functional polymers | Employed as a fluorinated aromatic acid in Suzuki coupling and related reactions to prepare compounds with tailored electro-optical properties |
| Research Reagents | Laboratory-scale synthesis of fine chemicals | Utilized in fluorine chemistry research for functional group transformations and structural modifications to support novel compound development |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~230 nm. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and identification/quantification of structurally related impurities (e.g., bromination by-products, hydrolysis products) using gradient elution and spectral or mass confirmation. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., dichloromethane, toluene, methanol) against calibrated standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification of trace heavy metals after acid digestion, leveraging high sensitivity and isotopic resolution for regulatory compliance (e.g., ICH Q3D). |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample moisture in anhydrous methanol-based medium. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Determination of inorganic ash content by ignition at 700–800 °C followed by precise weighing of residual inorganic material. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating; sharp melting range indicates crystalline purity and absence of significant eutectic impurities. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to detect chiral contamination (though compound is achiral, confirms absence of optically active impurities). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% |
| Melting Point | 142-146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Acid Value (mg KOH/g) | 230-245 mg KOH/g |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.