4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2836-44-4 |
| Product name | 4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Herbicide intermediate | Used in the synthesis of sulfonylurea herbicides such as trifloxysulfuron, via multi-step reactions including chlorination, amination, and sulfonylation to construct the pyrimidine ring side chain and sulfonamide bridge |
| Pharmaceuticals | Drug synthesis intermediate | Serves as a pyrimidine scaffold precursor for potential antibacterial or antiviral agents, participating in coupling, alkylation, or heterocycle construction reactions to functionalize the C2, C4, and C6 positions |
Manufacturing Quality Control of 4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection for volatile organic solvents (e.g., methanol, acetone, ethyl acetate) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to quantify water via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification after acid digestion, with detection limits <1 ppm for Pb, Cd, Hg, As, and others. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of inorganic residue after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Thermogravimetric Analysis | Mass loss measured under controlled heating (105 C, 2 h) to assess volatile content including moisture and residual solvents. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and absence of racemization. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine D10, D50, D90 values per ISO 13320. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH measurement of 1% w/v suspension in purified water using calibrated pH electrode per USP <791>. |
Technical Specifications of 4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 142–146°C |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE
Safety Information of 4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE
Industrial 4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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