China Factory Direct
|
|
| CAS number | 2840-28-0 |
| Product name | 3-Amino-4-chlorobenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of anti-inflammatory drug intermediates | Used as a key intermediate in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), such as piroxicam-class compounds |
| Pesticides | Synthesis of herbicides and fungicides | Applied as an organic synthesis intermediate to construct biologically active heterocyclic structures |
| Dyes | Synthesis of azo dyes | Participates in diazotization reactions for the preparation of azo dye compounds with specific molecular structures |
| Fine Chemicals | Organic synthesis intermediate | Undergoes acylation, substitution, and other reactions via its amino and carboxyl functional groups to produce functional chemicals |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | Determines the infrared absorption spectrum of the sample and compares it with the standard reference spectrum to confirm the presence of characteristic functional groups of 3-Amino-4-chlorobenzoic acid, such as carboxyl, amino, aromatic ring, and C–Cl bond absorption peaks. |
| High-Performance Liquid Chromatography (HPLC) Retention Time Comparison | Compares the retention time of the test sample with that of the reference substance under specific chromatographic conditions for preliminary identification. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with phosphate buffer-methanol or acetonitrile as the mobile phase and UV detection (typically around 254 nm). The content of the main component is calculated using external standard method. This method offers high specificity and good reproducibility, making it suitable for quantitative analysis of active pharmaceutical ingredients. |
| Acid-Base Titration | Utilizes the acidity of the carboxyl group; titrates with standardized sodium hydroxide solution in either non-aqueous or aqueous medium, determining the endpoint via potentiometry or indicator method, and calculates the content. Suitable for samples with high purity and minimal interfering impurities. | |
| Related Substances (Impurity Testing) | High-Performance Liquid Chromatography (HPLC) | Employs gradient or isocratic elution to separate and detect potential process-related impurities (e.g., unreacted raw materials, intermediates) and degradation products (e.g., dechlorinated or oxidized compounds). Quantification is typically performed using area normalization or the main component self-control method with correction factors. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Constant-Pressure Drying Method | Dries the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, measuring the percentage of mass loss to assess moisture and volatile substances content. |
| Residue on Ignition | Gravimetric Method | After high-temperature ignition (typically 700–800°C), the residual inorganic matter is weighed to control inorganic impurities (e.g., metal catalyst residues). |
| Residual Solvents | Gas Chromatography (GC) | Uses headspace injection or direct injection with polar or non-polar capillary columns and FID detection to determine organic solvents (e.g., toluene, dichloromethane, DMF) potentially remaining from synthesis processes. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After sample digestion, quantifies harmful elements such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmacopoeial limits. |
| pH Value | pH Meter Method | Prepares an aqueous solution of specified concentration (e.g., 1%), then measures its pH using a calibrated pH meter, reflecting the presence of free acid or basic impurities. |
| Test Item | Specification |
|---|---|
| Appearance | White to green to brown crystalline powder |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 175–179 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.