4-AMINO-2,3-DIFLUORO-5-NITRO-BENZOIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 284030-57-5 |
| Product name | 4-AMINO-2,3-DIFLUORO-5-NITRO-BENZOIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-AMINO-2,3-DIFLUORO-5-NITRO-BENZOIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-AMINO-2,3-DIFLUORO-5-NITRO-BENZOIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-AMINO-2,3-DIFLUORO-5-NITRO-BENZOIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediates in the synthesis of certain drug molecules | Nitration to introduce nitro groups under strongly acidic conditions; fluorination to introduce fluorine atoms using a specific catalyst; followed by amination to introduce amino groups. |
| Agrochemical Intermediates | Used in the synthesis of herbicidally active agrochemical compounds | Similar process sequence as in pharmaceutical applications, ensuring introduction and protection of key functional groups. |
| Materials Science | Functional monomer in organic synthetic materials | May involve multi-step reactions including fluorination, nitration, and amination; specific process parameters are adjusted according to the target material properties. |
Manufacturing Quality Control of 4-AMINO-2,3-DIFLUORO-5-NITRO-BENZOIC ACID
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and physical state (e.g., powder, crystalline) of the sample, checking for caking or visible impurities. It should typically be a pale yellow to yellow solid. |
| Assay/Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a mobile phase of methanol-water or acetonitrile-water (containing buffer salts such as phosphate or formic acid). Detect the main peak using a UV detector (typically within 254–365 nm range), and calculate the assay using external standard or area normalization methods. |
| Related Substances/Impurities | High-Performance Liquid Chromatography (HPLC) | Similar to assay determination, employ gradient elution to separate potential impurities such as synthesis intermediates, by-products, or degradation products (e.g., unreacted starting materials, deaminated compounds, reduction impurities), and evaluate individual and total impurity levels. |
| Water Content | Karl Fischer Titration | Quantitatively determine moisture content in the sample using Karl Fischer reagent, suitable for precise control of loss on drying in active pharmaceutical ingredients. |
| Residual Solvents | Gas Chromatography (GC) | In accordance with ICH guidelines, detect organic solvents possibly remaining from manufacturing processes (e.g., methanol, ethanol, dichloromethane, DMF), using headspace or direct solution injection with FID detection. |
| Melting Point | Melting Point Apparatus | Determine the initial and final melting temperatures using an automatic or manual melting point apparatus for identification and preliminary purity assessment. The compound is expected to exhibit a specific melting range. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Obtain infrared absorption spectra by pressing the sample with KBr or using an ATR accessory, then compare with reference spectra to confirm functional groups (e.g., —COOH, —NH₂, nitro, C—F bonds). |
| Nuclear Magnetic Resonance (NMR) | ¹H NMR and ¹⁹F NMR | Used for structural confirmation; dissolve the sample in deuterated DMSO or CDCl₃, and analyze chemical shifts, integration ratios, and coupling patterns in proton and fluorine NMR spectra to verify molecular structure. |
| Residue on Ignition/Sulfated Ash | Gravimetric Method | Weigh the inorganic residue after high-temperature incineration of the sample to assess inorganic impurity content. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Thioacetamide Method (Pharmacopoeial Method) | Detect heavy metal residues such as lead, cadmium, mercury, and arsenic. ICP-MS offers high sensitivity for trace analysis, while traditional methods rely on colorimetric reactions. |
Technical Specifications of 4-AMINO-2,3-DIFLUORO-5-NITRO-BENZOIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 178–182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-AMINO-2,3-DIFLUORO-5-NITRO-BENZOIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-AMINO-2,3-DIFLUORO-5-NITRO-BENZOIC ACID
Safety Information of 4-AMINO-2,3-DIFLUORO-5-NITRO-BENZOIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-AMINO-2,3-DIFLUORO-5-NITRO-BENZOIC ACID
Industrial 4-AMINO-2,3-DIFLUORO-5-NITRO-BENZOIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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