China Factory Direct
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| CAS number | 28664-35-9 |
| Product name | 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeCosmetic GradeFood Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Fragrance Industry | Used as a fragrance ingredient in perfume compounding | Extracted from fenugreek seeds or prepared via chemical synthesis |
| Pharmaceutical Industry | Used as a pharmaceutical intermediate in the synthesis of certain drugs | Produced via organic synthesis processes, such as esterification |
| Cosmetics Industry | Used in cosmetic formulations as a fragrance additive | Incorporated into cosmetics via dissolution or blending |
| Detection Item | Common Detection Methods | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reversed-phase column with mobile phases such as methanol-water or acetonitrile-water, and UV detection (e.g., 220 nm or 254 nm) for quantitative analysis of trigonelline content. This method offers high sensitivity and excellent reproducibility. |
| Purity Check | Thin Layer Chromatography (TLC) | Utilizes silica gel G plates with developing solvents such as petroleum ether-ethyl acetate systems. After development and visualization, the number and positions of spots are examined to assess impurities. The method is simple and rapid, suitable for preliminary purity screening. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | By analyzing chemical shifts, coupling constants, and other parameters in ¹H-NMR and ¹³C-NMR spectra, the molecular structure can be confirmed as trigonelline. This technique is considered the gold standard for structural identification. |
| Molecular Weight & Fragment Information | Mass Spectrometry (MS), such as GC-MS or LC-MS | Obtains molecular ion peaks and fragment ions via electron impact or electrospray ionization. Combined with accurate molecular weight and fragmentation patterns, it aids in qualitative identification and inference of impurity structures. |
| Volatile Impurities / Solvent Residues | Gas Chromatography (GC) | Used to detect residual organic solvents (e.g., ethanol, ethyl acetate) from synthesis or extraction processes. Employing capillary columns and FID detectors, results are controlled within pharmacopoeial limits. |
| Optical Purity / Optical Rotation | Optical Rotation Measurement | Trigonelline contains chiral centers. Measuring its specific rotation [α]D²⁵ allows assessment of optical purity, ensuring compliance with natural configuration or synthetic process requirements. |
| Drying Loss | Drying Method or Thermogravimetric Analysis (TGA) | Sample is dried at a specified temperature (e.g., 105°C) until constant weight. The percentage of mass loss is calculated to control moisture and volatile substance levels. |
| Residual Ash | High-Temperature Incineration Method | Sample is incinerated at high temperatures (e.g., 600–800°C), and the mass of inorganic residue is weighed. This evaluates levels of inorganic impurities or catalyst residues. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Odor | Characteristic sweet, maple-like odor |
| Optical Rotation | -15° to -25° (c=1 in ethanol) |
| Refractive Index (n20/D) | 1.515 to 1.525 |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.