4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-3,6-DIHYDRO-2H-PYRIDINE-1-CARBOXYLIC ACID BENZYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 286961-15-7 |
| Product name | 4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-3,6-DIHYDRO-2H-PYRIDINE-1-CARBOXYLIC ACID BENZYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 286961-15-7
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 286961-15-7 Supplier from China
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Industrial Applications of 286961-15-7
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Boronic ester protecting group (pinacol boronate) for Suzuki-Miyaura cross-coupling to construct pyridine-containing drug scaffolds | Under palladium catalysis (e.g., Pd(dppf)Cl₂), cross-couples with aryl or heteroaryl halides, followed by Cbz deprotection to yield target piperidine/tetrahydropyridine derivatives |
| Organic Synthesis | Multifunctional synthon featuring an N-Cbz-protected nitrogen atom and a C4 boronic ester functional group, enabling orthogonal control of nitrogen protection and carbon–carbon bond formation | Suzuki coupling is performed first to introduce substituents, followed by selective hydrogenolytic Cbz removal; alternatively, Cbz is removed first to generate the free amine, which is then acylated or alkylated, and the boronic ester subsequently participates in further coupling reactions |
| Materials Science | Potential organic optoelectronic material intermediate for constructing nitrogen-containing heterocyclic conjugated polymers or small-molecule acceptors | Undergoes Suzuki polycondensation with bromo- or iodo-substituted aromatic monomers to prepare π-conjugated backbones with tunable energy levels |
Manufacturing Quality Control of 286961-15-7
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by retention time and UV peak area against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, MeOH, EtOAc) based on flame ionization response. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration with iodine-based reagent. |
| Heavy Metals | ICP-MS | Quantifies trace metal contaminants (e.g., Pd, Ni, Fe) via mass spectrometric detection of elemental ions. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride anions using conductivity detection after ion exchange. |
| Residual Boron | ICP-OES | Measures total boron content by optical emission intensity at characteristic wavelengths. |
| Optical Rotation | [a]D Measurement | Determines specific rotation using sodium D-line light to assess chiral purity and enantiomeric excess. |
| Melting Point | Capillary Melting Point Apparatus | Identifies phase transition temperature range indicating crystallinity and purity. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension via angular scattering pattern analysis. |
| Bulk Density | USP <616> Tap Density Test | Determines mass per unit volume after standardized mechanical tapping of powder sample. |
| Microbial Limits | Membrane Filtration and Plate Count | Detects and enumerates aerobic microorganisms using filtration, membrane transfer, and colony growth enumeration. |
Technical Specifications of 286961-15-7
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 286961-15-7
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 286961-15-7
Packaging of 286961-15-7
Industrial 286961-15-7 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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