1-Boc-4-ethynylpiperidine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 287192-97-6 |
| Product name | 1-Boc-4-ethynylpiperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 1-Boc-4-ethynylpiperidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Boc-4-ethynylpiperidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Boc-4-ethynylpiperidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Key intermediate for synthesizing targeted therapeutics (e.g., kinase inhibitors, G protein-coupled receptor modulators) | Suzuki or Sonogashira cross-coupling to form C–C bonds; followed by Boc deprotection and functional group transformations |
| Agrochemical R&D | Structural motif in novel insecticides and fungicides, enhancing metabolic stability and target binding affinity | Alkyne participation in cycloaddition reactions (e.g., Click chemistry) to introduce triazole and other heterocyclic pharmacophores |
| Materials Science | Building block for functionalized organic light-emitting diode (OLED) hole-transport materials | Alkyne group used for terminal modification—grafted onto conjugated polymer backbones or small-molecule charge-transport layers to improve thin-film morphology and charge-carrier mobility |
Manufacturing Quality Control of 1-Boc-4-ethynylpiperidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase chromatography with UV detection at 210-230 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., Boc-deprotected, hydrolyzed, or dimerized species) using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Measures trace organic solvents (e.g., THF, DMF, ethyl acetate) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration where iodine reacts stoichiometrically with water in a pyridine/methanol solvent system. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pd, Ni, Fe, Cu) by inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection after aqueous extraction. |
| Residual Palladium | ICP-OES | Measures palladium residue from catalytic hydrogenation steps by inductively coupled plasma optical emission spectroscopy after microwave digestion. |
| Optical Rotation | [alpha]D | Determines specific optical rotation using a polarimeter at 20 °C with sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities affecting lattice stability. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring mass loss after drying under controlled temperature and vacuum for fixed duration. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension (e.g., 10 mg/mL in water) using calibrated pH electrode to assess acidic/basic degradation products. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension using Mie theory-based light scattering patterns generated by laser beam interaction. |
Technical Specifications of 1-Boc-4-ethynylpiperidine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 1-Boc-4-ethynylpiperidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-Boc-4-ethynylpiperidine
Packaging of 1-Boc-4-ethynylpiperidine
Industrial 1-Boc-4-ethynylpiperidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply