Cbz-Pro-Leu-OMe Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2873-37-2 |
| Product name | Cbz-Pro-Leu-OMe |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Cbz-Pro-Leu-OMe
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Cbz-Pro-Leu-OMe Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Cbz-Pro-Leu-OMe
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of pharmaceuticals, particularly antiviral drugs | Synthesized via multi-step organic reactions—including amidation and cyclization—by reacting (S)-2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylic acid tert-butyl ester with other compounds to construct the target drug molecule. |
| Chemical Research | Chiral ligand or catalyst in asymmetric synthesis | Employed as a chiral inducer in metal-catalyzed asymmetric transformations—such as asymmetric addition or substitution—to selectively generate single stereoisomers. |
| Biotechnology | Development of bioactive molecules | Used directly or after minimal modification as a potential bioactive component in drug discovery, including design and evaluation of enzyme inhibitors. |
Manufacturing Quality Control of Cbz-Pro-Leu-OMe
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~210–220 nm, comparing peak area against a qualified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment via separation on a chiral stationary phase (e.g., Chiralpak AD-H), with UV detection and comparison to (S,S)-reference standard. |
| Residual Solvents | GC-FID | Identification and quantification of ICH Class 2/3 solvents (e.g., THF, EtOAc, MeOH) using headspace GC with flame ionization detection. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content based on the stoichiometric reaction of iodine with water in a pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion, using isotopic detection with high sensitivity and low detection limits. |
| Residual Palladium | ICP-MS | Specific quantification of Pd residues (from prior asymmetric hydrogenation steps) following microwave-assisted acid digestion and isotopic analysis. |
| Related Substances | HPLC-UV (Forced Degradation Compatible) | Detection and quantification of structurally related impurities (e.g., diastereomers, hydrolysis/decarboxylation products) under stressed conditions (acid/base/oxidative/thermal). |
| Optical Rotation | [α]D Measurement | Determination of specific optical rotation at 589 nm (Na D-line) in specified solvent/concentration to confirm chiral integrity and batch consistency. |
| Residual tert-Butyl Alcohol | GC-FID | Quantification of residual t-BuOH (from incomplete deprotection or synthesis carryover) using calibrated headspace GC-FID. |
| Particle Size Distribution | Laser Diffraction | Measurement of dry powder particle size distribution (D10, D50, D90) to ensure consistent downstream processing (e.g., filtration, blending). |
Technical Specifications of Cbz-Pro-Leu-OMe
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 82.0–86.0°C |
| Optical Rotation | -25.0° to -29.0° (c=1, in CHCl3) |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Cbz-Pro-Leu-OMe
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Cbz-Pro-Leu-OMe
Packaging of Cbz-Pro-Leu-OMe
Industrial Cbz-Pro-Leu-OMe Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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