3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 287944-16-5 |
| Product name | 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates | Used in Suzuki coupling reactions |
| Agrochemicals | Synthesis of active pharmaceutical ingredients (APIs) | Applied in cross-coupling reactions involving boronate esters |
| Materials Science | Preparation of functionalized organic materials | Applied in organic boron-based chemical modification processes |
| Organic Synthesis | Construction of complex molecular frameworks | Applied in carbon–carbon bond-forming reactions |
Manufacturing Quality Control of 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities (e.g., residual starting materials, deboronated by-products, isomers) using gradient HPLC-UV with identification via retention time matching and threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., THF, toluene, ethanol) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content based on stoichiometric reaction of iodine with water in anhydrous methanol/pyridine medium. |
| Heavy Metals | ICP-MS | Quantification of elemental impurities (e.g., Pd, Ni, Fe) using inductively coupled plasma mass spectrometry with isotope dilution for high sensitivity and specificity. |
| Residual Palladium | ICP-MS | Targeted quantification of palladium from Suzuki coupling catalyst residues using ICP-MS with internal standard correction (e.g., Rh or In). |
| Appearance and Color | Visual Inspection / APHA Color Scale | Subjective visual assessment against water-white reference; color quantified by APHA (Platinum-Cobalt) scale using spectrophotometric measurement. |
| Melting Point | DSC | Thermal analysis by differential scanning calorimetry to determine onset and range of solid–liquid phase transition, confirming crystallinity and identity. |
| Specific Optical Rotation | [α]D | Polarimetric measurement at 589 nm (Na D-line) to confirm chiral integrity and absence of racemization during synthesis/handling. |
| Particle Size Distribution | Laser Diffraction | Dry or wet dispersion followed by laser light scattering to determine volume-based particle size distribution (D10, D50, D90) relevant for formulation handling. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a standardized suspension (e.g., 1% w/v in water) to assess acid/base impurities affecting stability and reactivity. |
| Residual Boric Acid Derivatives | Ion Chromatography (IC) with Conductivity Detection | Separation and quantification of borate species (e.g., boric acid, sodium borate) via anion-exchange chromatography and suppressed conductivity detection. |
| Loss on Drying (LOD) | Gravimetric Thermogravimetry | Weight loss measured after controlled heating (e.g., 105 °C, 2 h) under dry nitrogen, indicating volatile content including solvates and moisture. |
| Microbial Limits | Membrane Filtration + TSA/SDA | Enumeration of aerobic bacteria, yeasts, and molds using membrane filtration followed by incubation on Tryptic Soy Agar and Sabouraud Dextrose Agar per USP <61>. |
Technical Specifications of 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 65–69°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester
Safety Information of 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester
Industrial 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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