China Factory Direct
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| CAS number | 288-36-8 |
| Product name | 1,2,3-1H-Triazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antiviral drug intermediates | Used as a 1,2,4-triazole ring building block in nucleoside analog synthesis for anti-HIV and anti-hepatitis B drugs |
| Agrochemicals | Intermediate for fungicides and plant growth regulators | Applied in the synthesis of triazole-containing agrochemicals for crop fungal disease control |
| Fine Chemicals | Organic synthesis intermediate | Reacted with alkynes via copper-catalyzed azide–alkyne cycloaddition (CuAAC) to prepare 1,4-disubstituted triazole compounds |
| Materials Science | Functional modifier for polymers | Used to functionalize polymer chain ends or side chains, enhancing thermal stability and polarity |
| Analytical Chemistry | Chelating agent for metal ions | Coordinates with transition metals such as copper and zinc via its polyazide structure for sensor or assay reagent preparation |
| Milestone | Common Testing Methods | Method Overview |
|---|---|---|
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Using a reverse-phase column, with a mobile phase of methanol/water or acetonitrile/buffer salt, and a UV detector (e.g., 210–254 nm) for quantification of the main component purity and separation of impurity peaks. |
| Content Determination | HPLC External Standard Method / Titration | HPLC External Standard Method: Establishing a calibration curve using a standard solution of known concentration to calculate the sample content; Titration: Acid-base titration or non-aqueous titration to determine total alkaloid content. |
| Related Substances (Impurities) | HPLC Gradient Elution Method | Optimizing the gradient program to improve impurity resolution, detecting and quantifying process impurities and degradation products, typically setting a reporting threshold (e.g., 0.1%). |
| Water Content | Karl Fischer Titration | Measuring trace water using volumetric or coulometric methods, suitable for thermally unstable or hygroscopic compounds. |
| Residual Solvents | Gas Chromatography (GC-FID/HS-GC) | Headspace or direct injection, with FID detection to analyze residual organic solvents (e.g., methanol, ethanol, DMF), in accordance with ICH Q3C guidelines. |
| Melting Point | Capillary Melting Point Apparatus | Determining the temperature range from initial melting to complete melting to assess crystallinity and polymorphic consistency, with a theoretical melting point of approximately 119–121°C for 1,2,3-triazole. |
| Appearance | Visual Inspection | Observing the sample's color (should be white to off-white), crystal form, presence of foreign matter, or lumping in physical state. |
| pH Value (Solution) | pH Meter Measurement | Preparing an aqueous solution of a certain concentration (e.g., 1% w/v) to measure pH value, assessing its acidity or alkalinity and impact on formulation stability. |
| Ignition Residue | Weight Method (High-Temperature Ashing) | Charring the sample in a muffle furnace at 600–800°C until constant weight, measuring the amount of inorganic impurities, generally requiring ≤0.1%. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determining residual heavy metals such as lead, cadmium, mercury, and arsenic after digestion, in compliance with pharmacopoeia or ICH Q3D limits. |
| Test Item | Specification |
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| Appearance | Colorless liquid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 22-24°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Odor | Characteristic odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.