2-CHLORO-5-IODOPHENOL Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 289039-26-5 |
| Product name | 2-CHLORO-5-IODOPHENOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-CHLORO-5-IODOPHENOL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-CHLORO-5-IODOPHENOL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-CHLORO-5-IODOPHENOL
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used in the synthesis of thyroid hormone receptor agonists or antagonists | Employed as an intermediate to construct aromatic frameworks via Suzuki coupling |
| Pharmaceuticals | Used in the preparation of anti-infective or anticancer agents | Applied to introduce bioactive molecular structures via nucleophilic substitution or metal-catalyzed coupling reactions |
| Chemical | Used in the synthesis of novel organic functional materials or dyes | Utilized as a precursor for functional group transformations or polymerization reactions |
| Research | Used in the development of novel biologically active probes | Applied to label biomolecules via click chemistry or coupling reactions |
Manufacturing Quality Control of 2-CHLORO-5-IODOPHENOL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~280 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-DAD or UPLC-MS | Separation and identification/quantification of structurally related impurities (e.g., 2-chloro-3-iodophenol, 2-chloro-4-iodophenol, residual starting materials) using gradient elution and spectral or mass confirmation. |
| Residual Solvents | GC-FID | Headspace GC analysis with flame ionization detection to quantify common process solvents (e.g., methanol, acetone, ethyl acetate, toluene) against calibrated standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after acid digestion and dilution; provides sub-ppb sensitivity and compliance with ICH Q3D elemental impurity limits. |
| Chloride Content | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions released via alkaline hydrolysis or direct extraction, enabling trace-level quantification. |
| Iodine Content | Potentiometric Titration with Sodium Thiosulfate | Oxidative liberation of iodine (e.g., using bromine water), followed by back-titration of excess oxidant or direct titration of liberated I₂ with standardized thiosulfate. |
| Moisture Content | Karl Fischer Coulometric Titration | Electrochemical generation and stoichiometric reaction of iodine with water in anhydrous medium; suitable for low-moisture solids (<0.1%). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated digital apparatus per USP <741>; indicative of crystalline purity and identity. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | High-temperature incineration (500–600 °C) of sample followed by weighing of non-volatile inorganic residue; assesses inorganic impurity load. |
| Appearance and Color | Visual Inspection & APHA Color Scale | Subjective evaluation of crystalline form and color intensity against platinum-cobalt standards; detects degradation or contamination. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using Mie theory to determine D10, D50, D90 values; relevant for downstream processing consistency. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at specified wavelength (e.g., 589 nm) and temperature; confirms chiral integrity (though compound is achiral, used to detect chiral contaminants). |
Technical Specifications of 2-CHLORO-5-IODOPHENOL
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown solid |
| Purity | >=98.0% |
| Melting Point | 72–76 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Identification (NMR) | Conforms to reference standard |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-CHLORO-5-IODOPHENOL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-CHLORO-5-IODOPHENOL
Packaging of 2-CHLORO-5-IODOPHENOL
Industrial 2-CHLORO-5-IODOPHENOL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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