China Factory Direct
|
|
| CAS number | 29022-11-5 |
| Product name | Fmoc-Gly-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceutical R&D | Peptide synthesis reagent | Used as an Fmoc-protected glycine derivative for N-terminal protection and coupling reactions in solid-phase peptide synthesis |
| Biochemistry | Protein structure studies | Introduced as a structural building block during synthesis of functional peptide segments |
| Organic synthesis | Amino acid derivative preparation | Employed as the Fmoc-protected form of glycine for constructing organic synthesis intermediates |
| Analytical chemistry | Peptide reference standard synthesis | Used to synthesize peptide reference standards for mass spectrometry or chromatographic analysis |
| Chemical industry | Synthetic resins and polymers | Incorporated as a crosslinking or functional group unit in the synthesis of certain functional resins or polymers |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible impurities. Fmoc-glycine is typically a white to off-white powder. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Reverse-phase HPLC (e.g., C18 column) with UV detection (~265 nm); purity calculated based on the main peak area, typically requiring ≥98% or ≥99%. |
| Chiral Purity | Chiral HPLC or Capillary Electrophoresis | Detects the presence of D-isomer impurities to ensure L-isomer purity; used for chiral control of amino acid compounds. |
| Moisture Content | Karl Fischer Titration | Accurately measures moisture content in the sample, typically requiring ≤0.5%. |
| Residual Solvents | Gas Chromatography (GC) | Detects organic solvents possibly remaining from synthesis (e.g., DMF, toluene, ethyl acetate), in compliance with pharmacopoeial or ICH guidelines. |
| Melting Point | Melting Point Apparatus | Determines the melting temperature range; the typical melting point of Fmoc-glycine is approximately 218–222°C (with decomposition). |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Compare with reference spectra to verify functional groups (e.g., amide bond, Fmoc aromatic ring, carboxyl group) are consistent with expected structure. |
| Nuclear Magnetic Resonance (NMR) | ¹H-NMR and ¹³C-NMR | Measured in deuterated solvents (e.g., DMSO-d6) to confirm molecular structure and identify impurity signals; used for structural verification and as an auxiliary method for purity assessment. |
| UV Absorption | UV-Visible Spectrophotometry | Exhibits characteristic absorption near 265 nm; useful for quantitative analysis or as a reference for HPLC detection. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detects residual heavy metals such as lead, mercury, cadmium, and arsenic; must meet pharmaceutical or high-purity reagent standards (e.g., ≤10 ppm). |
| Residue on Ignition / Sulfated Ash | Gravimetric Analysis | Weighing residue after high-temperature ignition to assess inorganic impurity content, typically requiring ≤0.1%. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 136–140°C |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | -15° to -21° (c=1, in DMF) |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.