China Factory Direct
|
|
| CAS number | 29169-64-0 |
| Product name | (R)-(-)-O-Formylmandeloyl chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral drug intermediates | Used in the synthesis of optically active chiral drugs such as β-blockers, forming amide bonds via reaction with amines |
| Fine chemicals | Chiral synthetic reagents | Employed as a chiral acyl chloride in asymmetric synthesis to introduce (R)-mandelic acid-derived structural motifs |
| Pesticides | Pesticide intermediates | Applied in the preparation of pesticide active ingredients with defined stereochemistry to enhance selectivity and biological activity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with Chiral Column | Separation and quantification of (R)-(-)-O-formylmandelic acid chloride enantioselectively using a chiral stationary phase and UV detection. |
| Optical Rotation | [α]D Measurement | Determination of specific optical rotation at 589 nm to confirm enantiomeric identity and purity based on chiral center integrity. |
| Residual Solvents | GC-FID | Quantitative analysis of volatile organic solvents (e.g., dichloromethane, toluene) using flame ionization detection after headspace or direct injection. |
| Acid Chloride Content | Potentiometric Titration with Standardized NaOH (back-titration after hydrolysis) | Hydrolysis of acid chloride to carboxylic acid followed by titration; acid chloride concentration calculated from consumed base. |
| Water Content | Karl Fischer Coulometric Titration | Electrochemical quantification of water via iodine generation in anhydrous methanol-based reagent, suitable for low-water samples (<1000 ppm). |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Hg, Ni) after microwave-assisted acid digestion and isotopic dilution calibration. |
| Related Substances (Impurities) | HPLC-UV (Achiral) | Separation and detection of structurally related impurities (e.g., unreacted acid, O-formylmandelic acid, mandelic acid, acyl chloride dimers) using reversed-phase C18 column. |
| Chloride Ion (Inorganic Chloride) | Ion Chromatography with Conductivity Detection | Quantitative determination of free Cl⁻ arising from hydrolysis or synthesis residues using anion-exchange column and suppressed conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after controlled high-temperature incineration (700–800 °C) and weighing. |
| Appearance and Color | Visual Inspection & APHA Color Scale | Subjective assessment of physical state (white to off-white crystalline solid) and quantitative color comparison against platinum-cobalt standards. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating purity and identity (expected ~45–48 °C). |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow clear liquid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | -180.0 to -173.0 deg (c=1, in CHCl3) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.