China Factory Direct
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| CAS number | 2922-40-9 |
| Product name | 4-NITRO-DL-PHENYLALANINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical R&D | Used as a non-natural amino acid in the synthesis and modification of peptide therapeutics | Prepared via chemical synthesis involving Knoevenagel condensation of 4-nitrobenzaldehyde with diethyl acetamidomalonate, followed by hydrolysis, decarboxylation, and reduction |
| Biochemical Research | Employed as a precursor for fluorescent probes or as a photo-crosslinking reagent in enzymology studies | Leverages the photolability of the nitro group to achieve covalent crosslinking of protein–ligand interactions under UV irradiation |
| Chemical Synthesis | Serves as a chiral intermediate for synthesizing bioactive molecules containing the 4-nitrophenylalanine motif | Optically pure 4-nitro-DL-phenylalanine derivatives are obtained via asymmetric hydrogenation or enzymatic resolution |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification by reverse-phase HPLC with UV detection at 254 nm, using external standard calibration. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV against reference standards. |
| Residual Solvents | GC-FID | Detection and quantification of common solvents (e.g., methanol, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content. |
| Heavy Metals | ICP-OES | Multi-element determination of Pb, Cd, Hg, As, and others after acid digestion, based on atomic emission intensity. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-750 C followed by weighing of non-volatile inorganic residue. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using sodium D-line light in solution at specified concentration and temperature. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change under controlled heating rate. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measurement of hydrogen ion activity using calibrated glass electrode in a saturated aqueous suspension. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to derive volume-based particle size distribution. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms following filtration, membrane transfer, and incubation on soybean-casein digest agar. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 210-215°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.