2,4-Dichloro-5-fluoropyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2927-71-1 |
| Product name | 2,4-Dichloro-5-fluoropyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,4-Dichloro-5-fluoropyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,4-Dichloro-5-fluoropyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,4-Dichloro-5-fluoropyrimidine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Fungicide intermediate | Used in the synthesis of fungicides such as trifloxystrobin |
| Pharmaceuticals | Intermediate for antibiotics or antiviral agents | Serves as a raw material in the synthesis of certain antibiotics or antiviral drugs |
| Chemical manufacturing | Synthesis of other chlorinated/fluorinated heterocyclic compounds | Functions as a key organic synthetic intermediate in multiple reactions |
Manufacturing Quality Control of 2,4-Dichloro-5-fluoropyrimidine
| Test Item | Common Test Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection Method | Observe the sample's color, physical state (e.g., white or off-white crystalline powder), and presence of foreign matter with the naked eye to determine if it meets quality standards. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) |
- IR: Measure the infrared absorption spectrum of the sample and compare it with that of the reference standard to confirm consistency of characteristic functional groups (e.g., C–F, C–Cl, pyrimidine ring). - HPLC: Under specified chromatographic conditions, compare the retention time of the main peak between the test sample and the reference standard. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a mobile phase of methanol-water or acetonitrile-buffer salt solution. Detection is performed using a UV detector (typically at around 254 nm), and the content of 2,4-dichloro-5-fluoropyrimidine is calculated using the external standard method, with a typical requirement of ≥98.0%. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Using gradient or isocratic elution, separate and detect possible organic impurities (e.g., unreacted starting materials, by-products, degradation products). The individual and total impurity levels are controlled using the area normalization method or self-reference method (e.g., individual impurity ≤0.5%, total impurities ≤1.0%). |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection is used with a polar or non-polar capillary column and an FID detector to detect residual organic solvents possibly present from the manufacturing process (e.g., dichloromethane, toluene, ethanol). Limits are controlled according to ICH Q3C guidelines. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Ordinary Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, and measure the percentage of mass loss due to moisture or other volatile components, typically required to be ≤0.5%. |
| Melting Point | Capillary Melting Point Determination | Determine the temperature range from initial melting to complete melting using a melting point apparatus. The typical melting point of 2,4-dichloro-5-fluoropyrimidine is approximately 70–74°C, used for auxiliary identification and purity assessment. |
| Water Content | Karl Fischer Titration | Determine the water content in the sample using volumetric or coulometric methods. This method is suitable for moisture-sensitive intermediates or active pharmaceutical ingredients, typically required to be ≤0.2%. |
Technical Specifications of 2,4-Dichloro-5-fluoropyrimidine
| Test Item | Specification |
|---|---|
| Appearance | Gray solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 68–72°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,4-Dichloro-5-fluoropyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,4-Dichloro-5-fluoropyrimidine
Safety Information of 2,4-Dichloro-5-fluoropyrimidine
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2,4-Dichloro-5-fluoropyrimidine
Industrial 2,4-Dichloro-5-fluoropyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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