(1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2964-48-9 |
| Product name | (1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediates or synthetic raw materials for anti-tuberculosis antibiotics such as L-DOPA and chloramphenicol | Chemical synthesis |
| Pharmaceuticals | Synthesis of D-(−)-threo-2-amino-1-(4-nitrophenyl)-1,3-propanediol (DAN) | Chemical synthesis |
| Chemicals | Chiral reagent or resolving agent | Separation and purification |
Manufacturing Quality Control of (1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, caking, and presence of visible impurities under natural or standard lighting. This compound is typically a white to off-white solid. |
| Identification (Structural Confirmation) | Nuclear Magnetic Resonance Spectroscopy (NMR) Infrared Spectroscopy (IR) Mass Spectrometry (MS) |
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| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase HPLC (e.g., C18 column) with gradient elution of water and organic solvents (e.g., methanol or acetonitrile), and UV detection (typically at 254 nm or 280 nm) to assess main peak purity. Calculate normalized peak area purity and evaluate levels of related substances. |
| Related Substances (Impurities) | HPLC or UPLC | Same as above; identify and quantify process impurities, degradation products, or isomers (e.g., diastereomers or enantiomeric impurities) by retention time. Impurity structures may be confirmed with mass spectrometry when necessary. |
| Enantiomeric Purity (Stereochemical Purity) | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Use chiral stationary phase columns (e.g., Chiralpak AD-H, AS-H) to separate and detect potential isomeric impurities such as (1R,2R), (1R,2S), (1S,2R), and determine enantiomeric excess (ee value). |
| Water Content | Karl Fischer Titration | Determine the content of adsorbed or crystalline water accurately using coulometric or volumetric Karl Fischer titration, ensuring compliance with loss on drying requirements. |
| Residual Solvents | Gas Chromatography (GC) | Detect solvents possibly remaining from manufacturing processes (e.g., methanol, ethanol, ethyl acetate, dichloromethane) using gas chromatography with FID detection, and control within limits specified by ICH Q3C guidelines. |
| Sulfated Ash (Residue on Ignition) | Residue on Ignition Test | Take a certain amount of sample, add sulfuric acid, then ignite at high temperature (about 600–800°C), and weigh the residual inorganic matter to assess inorganic impurity content. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After digesting the sample, use AAS or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) to detect heavy metal elements such as lead, cadmium, mercury, and arsenic, ensuring compliance with pharmacopoeial standards or ICH Q3D limits. |
| Melting Point | Melting Point Determination | Determine the melting temperature range using an automated or capillary melting point apparatus. Used as a physical reference to assist in assessing purity and crystal form consistency. |
Technical Specifications of (1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow powder or crystals |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152 °C |
| Optical Rotation | +29.0 to +33.0 ° (c=1, in methanol) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol
Safety Information of (1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol
Industrial (1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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