2-Aminothiazole-4-acetic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 29676-71-9 |
| Product name | 2-Aminothiazole-4-acetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Aminothiazole-4-acetic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Aminothiazole-4-acetic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Aminothiazole-4-acetic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antibacterial agents, used in the synthesis of cephalosporin antibiotics (e.g., cefazoxime sodium) | Condensed with acyl chlorides or acid anhydrides, followed by cyclization and hydrolysis to construct the β-lactam core structure |
| Pesticides | Intermediate for fungicides and insecticides, used in the synthesis of thiazole-based agrochemicals | Participates in coupling or cyclization reactions to prepare thiazole-ring-containing active ingredients (e.g., analogues of thiophanate-copper) |
| Dyes | Functional dye intermediate, used in the development of metal-complex dyes and fluorescent probes | Introduces chromophores via diazotization–coupling or condensation with aldehydes, enhancing photostability and metal-coordination capability |
Manufacturing Quality Control of 2-Aminothiazole-4-acetic acid
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Characteristics | Visual Inspection + Microscopic Observation | Observe color, crystal form, and presence of foreign particles. Typically appears as a white to off-white crystalline powder with no visible impurities. |
| Melting Point | Capillary Melting Point Method (GB/T 617) | Determine the melting temperature range under standard conditions. The typical melting point is 220–225 °C (decomposition), used for initial identification and purity assessment. |
| Content Determination (Active Pharmaceutical Ingredient) | High-Performance Liquid Chromatography (HPLC) | Use a C18 column with mobile phase consisting of methanol-water (containing 0.1% formic acid or phosphate buffer), UV detection at 210–220 nm, and external standard method for quantification. High accuracy, suitable for main component quantification in the presence of impurities. |
| Related Substances (Impurity Profile) | HPLC-UV or HPLC-MS | Same chromatographic conditions as content determination. Detect impurity peak areas using either the self-reference method or external standard method for impurity quantification; limit typically ≤1.0%. MS is used for preliminary structural identification of impurities. |
| Water Content | Karl Fischer Titration (KF Method) | Determine trace moisture using coulometric or volumetric Karl Fischer titration. Water content controlled at ≤0.5% to prevent hydrolysis or stability issues during storage. |
| Residual Solvents | Gas Chromatography (GC) | Per ICH Q3C guidelines, detect common organic solvent residues such as ethanol, acetone, ethyl acetate. Use headspace injection or direct injection with FID detection; limits meet pharmacopoeial requirements. |
| Heavy Metals (Pb, Cd, etc.) | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After acid digestion, determine lead, cadmium, and other heavy metal levels. Typical limit ≤10 ppm, compliant with pharmaceutical raw material standards. |
| Chloride, Sulfate | Turbidimetry or Ion Chromatography | Chloride determined by silver nitrate turbidimetry; sulfate by barium chloride turbidimetry; alternatively, ion chromatography for direct anion quantification. Controlled at ≤0.02%. |
| pH Value (Aqueous Solution) | pH Meter Method | Prepare a 1% aqueous solution of the sample and measure pH. Typically ranges from 5.0 to 7.0, reflecting acidity/basicity and potential for hydrolysis. |
| Particle Size Distribution (if applicable) | Laser Diffraction or Microscopic Sieving | For powder formulation raw materials, assess particle size distribution to ensure flowability and solubility. D90 typically ≤100 μm. |
| Nitrogen Content (Elemental Analysis) | Kjeldahl Nitrogen Method or Elemental Analyzer | Used to verify nitrogen content corresponding to amino groups (theoretical nitrogen content ~14.5%), supporting structural confirmation and synthetic process validation. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Compare with reference spectrum to confirm characteristic functional group absorption peaks (e.g., –NH₂ at ~3300 cm⁻¹, C=O at ~1710 cm⁻¹, thiazole ring at 1500–1600 cm⁻¹), used for structural verification. |
| Nuclear Magnetic Resonance (¹H NMR / ¹³C NMR) | Solution NMR Spectroscopy | Use DMSO-d₆ or D₂O as solvent; confirm structure based on characteristic proton chemical shifts (e.g., H-5 of thiazole ring, –CH₂COOH, –NH₂), serving as a high-level identification method with auxiliary purity evaluation. |
Technical Specifications of 2-Aminothiazole-4-acetic acid
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% |
| Melting Point | 178–182 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Aminothiazole-4-acetic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Aminothiazole-4-acetic acid
Safety Information of 2-Aminothiazole-4-acetic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Aminothiazole-4-acetic acid
Industrial 2-Aminothiazole-4-acetic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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