4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 29681-43-4 |
| Product name | 4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the anticancer drug irinotecan | Used to construct the 4-methoxypyridinecarboxylate side chain of irinotecan via esterification with 10-hydroxycamptothecin |
| Pharmaceuticals | Structural building block for candidate selective α7 nicotinic acetylcholine receptor (α7 nAChR) agonists | Employed in multi-step transformations—including hydrolysis and amide coupling—to introduce nitrogen-containing heterocyclic pharmacophores |
| Pesticides | Precursor to the picolinic ester moiety in novel insecticidal molecules | Applied to construct amide or oxime derivatives bearing a methoxypyridyl group, conferring targeted inhibitory activity against insect neuronal transmission |
Manufacturing Quality Control of 4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold limits. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, dichloromethane) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 700-800 C followed by sulfuric acid treatment and weighing of residual inorganic ash. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed via capillary method using calibrated instrument per USP <741>. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to assess chiral purity and identity. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against defined standards under controlled lighting conditions. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of pH in a saturated aqueous suspension using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser diffraction to obtain D10, D50, D90 values per ISO 13320. |
Technical Specifications of 4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
Safety Information of 4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
Industrial 4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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