China Factory Direct
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| CAS number | 2973-80-0 |
| Product name | 2-BROMO-5-HYDROXYBENZALDEHYDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of antitumor agents, antimicrobial agents, and selective estrogen receptor modulators (SERMs) | Serves as a key aromatic ring-building unit, incorporated into target molecular scaffolds via transition-metal-catalyzed reactions such as Suzuki coupling, Heck reaction, or reductive amination |
| Agrochemical Intermediates | Used in the preparation of novel fungicides and plant growth regulators | Undergoes selective bromine substitution or hydroxyl protection/deprotection, followed by condensation or alkylation with heterocyclic compounds to construct biologically active benzimidazole or triazole derivatives |
| Organic Synthesis | Functions as a multifunctional, functionalized aromatic aldehyde in transformations including Wittig reaction, Knoevenagel condensation, and reductive amination | The aldehyde group undergoes nucleophilic addition; the bromine atom acts as a leaving group for nucleophilic substitution or metalation (e.g., with Mg or Zn); the hydroxyl group can be selectively protected (e.g., acetylation or benzylation) to control reaction site selectivity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient HPLC-UV; identification based on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone, ethyl acetate) by headspace GC with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generated electrochemically in pyridine-free reagent. |
| Heavy Metals | ICP-OES | Quantifies metals (e.g., Pb, Cd, Ni, Fe) after acid digestion by measuring atomic emission intensities at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion-exchange column separation. |
| Sulfated Ash | Gravimetric Analysis | Measures non-volatile inorganic residue after combustion at 700-800 C in sulfuric acid medium, followed by weighing of residual ash. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube and controlled heating ramp. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under standardized white light and against specified reference standards. |
| Loss on Drying | Thermogravimetric Analysis | Measures mass loss after drying at 105 C for 2 hours, reflecting volatile content including moisture and low-boiling residues. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a saturated aqueous suspension (1:10 w/v) using calibrated pH electrode and buffer standards. |
| Specific Optical Rotation | Polarimetry | Determines chiral purity by measuring rotation angle of plane-polarized light through a solution in specified solvent and concentration. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 75–79°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.