Thiazolyl Blue Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 298-93-1 |
| Product name | Thiazolyl Blue |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Thiazolyl Blue
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Thiazolyl Blue Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Thiazolyl Blue
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Cell viability assay (MTT method) | Add MTT (thiazolyl blue) to live cell cultures; mitochondrial dehydrogenases reduce yellow MTT to purple formazan crystals, which are dissolved in dimethyl sulfoxide (DMSO) and quantified by spectrophotometry at 570 nm to determine viable cell count. |
| Drug Discovery | Anticancer drug screening and efficacy evaluation | Perform MTT assay on in vitro cell models following co-treatment with test compounds to assess inhibition of cancer cell proliferation (IC50 determination). |
| Toxicology Research | Cellular toxicity assessment of chemical substances | Conduct MTT assay per OECD Test Guideline 429 to evaluate cytotoxicity of test substances against standard cell lines (e.g., L929, HEK293) and establish safe concentration ranges. |
| Basic Medical Research | Mechanistic studies of apoptosis, autophagy, and signaling pathways | Use as a live-cell quantitative reference to normalize cell number differences between experimental and control groups when combined with flow cytometry, Western blotting, and other techniques—enhancing reliability of mechanistic data. |
Manufacturing Quality Control of Thiazolyl Blue
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and physical state of the sample. Qualified MTT should be a yellowish or purplish-red powder, free from caking and visible impurities. |
| Purity (Assay) | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Determine MTT concentration based on its absorbance at a specific wavelength (e.g., around 490 nm), and calculate purity using a standard calibration curve. |
| High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (typically at 254 nm or 490 nm) to quantify the main component and impurities by retention time and peak area, thereby assessing purity. | |
| Solubility | Solubility Test | Dissolve MTT in specified solvents (e.g., PBS, ethanol, DMSO), observe dissolution rate and solution clarity to evaluate whether solubility meets requirements. |
| Maximum Absorption Wavelength (λmax) | UV-Visible Spectral Scanning | Scan the absorption spectrum of an MTT solution between 200–600 nm to confirm that the maximum absorption peak is near the theoretical value (approximately 490 nm). |
| Moisture Content | Karl Fischer Titration | Precisely measure moisture content in the sample to ensure it remains within specified limits (typically ≤5.0%) and prevent degradation due to hygroscopicity. |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Detect residual levels of harmful metals such as lead, mercury, cadmium, and arsenic to ensure compliance with pharmacopoeial or reagent-grade standards. |
| Melting Point | Melting Point Determination (Capillary Method) | Determine the melting range of MTT (literature value approximately 170–175°C with decomposition), used for preliminary identification of chemical consistency. |
| Related Substances (Impurities) | HPLC Method | Separate MTT from its degradation products (e.g., formazan) using gradient elution, then calculate the percentage of impurity peak areas to control total impurity levels. |
| Microbial Limits | Microbial Limit Test | Perform tests for total aerobic microbial count, mold and yeast count, and specified controlled microorganisms according to the Chinese Pharmacopoeia or relevant standards to ensure sterility or compliance with acceptable limits. |
Technical Specifications of Thiazolyl Blue
| Test Item | Specification |
|---|---|
| Appearance | Yellow-green solid |
| Purity | >=98.5% (HPLC) |
| Melting Point | 203-207°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Solubility | Soluble in DMSO and DMF; slightly soluble in ethanol; insoluble in water |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Thiazolyl Blue
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Thiazolyl Blue
Packaging of Thiazolyl Blue
Industrial Thiazolyl Blue Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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